Two hundred highly-skilled jobs are to be created in Dublin over the next three years.
US software company Workday is to open a new European headquarters in Smithfield.
The California-based firm already employs nearly 400 staff in Dublin, having set up its European headquarters here in 2008.
The company creates cloud-computing applications for human resources and finances, providing services to more than 1,000 organisations globally.
Today, it is announcing the opening of a new office for its European headquarters in Smithfield, as well as plans to take on another 200 employees.
The new roles will be in product and technology development, data centre operations, customer support and sales.
Recruitment for the positions is already under way.
Taoiseach Enda Kenny said: "The continued investment in our economy by the likes of Workday is a vote of confidence in the Irish economy and our talented workforce."
In terms of local community I'm delighted to see Workday's commitment to corporate social responsibility-Tánaiste pic.twitter.com/g5qhNsWVW9— MerrionStreet.ie (@merrionstreet) October 7, 2015
Minister for Jobs Richard Bruton met senior Workday executives at their Californian HQ to discuss expansions in Ireland.
He said: "Cloud computing is a sector which we have targeted as part of our Action Plan for Jobs, and Workday's continued drive to create jobs in Dublin related to this area, and building on its previous commitments, is a major boost."
Workday's Chief Technology Officer in the EMEA, Annrai O'Toole, said: "Dublin is a growing hotbed of highly motivated, highly skilled technologists and we are actively expanding our team to drive our growth and customer success."