Patricia Dowdy, Stephen Hawking's former nurse, has been struck off the nursing register in the UK after the Nursing and Midwifery Council found that she "failed to provide the standards of good, professional care that we expect and Professor Hawking deserved".
Professor Hawking, one of the world's finest scientific minds, died last year at the age of 76.
The NMC said Mrs Dowdy had faced multiple misconduct charges in relation to the care she was providing to Prof Hawking - including, financial misconduct, dishonesty, not providing appropriate care and failing to cooperate with the NMC and not having the correct qualifications.
Matthew McClelland, director of Fitness to Practise at the NMC, said: "The panel has found Mrs Dowdy failed to provide the standards of good, professional care that we expect and Professor Hawking deserved.
"As a result, Mrs Dowdy will no longer be able to practice as a nurse.
"As the public rightly expects, in serious cases such as this - where a nurse has failed in their duty of care and has not been able to evidence to the panel that they have learned from their mistakes and be fit to practise - we will take action.
"We have remained in close contact with the Hawking family throughout this case and I am grateful to them - as they approach the anniversary of Professor Hawking's death - and others for sharing their concerns with us. My thoughts are with the family at this difficult time.
"As the regulator, we will always listen when concerns about the fitness of nurses, midwives or nursing associates are raised with us so that we can investigate further for the benefit of everyone involved."
Responding to the decision, a spokesman for the family said: "The Hawking family are relieved this traumatic ordeal has now concluded and that as a result of the verdict, others will not have to go through what they suffered from this individual.
"They want to thank the NMC for their thorough investigation."
The physicist and cosmologist was diagnosed with amyotrophic lateral sclerosis (ALS), a form of motor neurone disease, when he was a 22-year-old student at Cambridge University.
Most people die within a few years of the diagnosis.
After catching pneumonia in 1985, Prof Hawking needed around-the-clock care and relied on a computer and voice synthesizer to speak.
He died peacefully at his home in Cambridge on 15 March 2018.