American Airlines is to close its International Reservations Office in Dublin with the loss of 130 jobs.
The airline has operated a call centre there for the past 15 years.
In a statement the airline said it had 'posted significant losses in recent years; particularly compared to its US competitors which benefitted from reducing costs through the bankruptcy courts.'
It said the outsourcing from Dublin of the 130 jobs could result in 'significant savings' for the airline.
It said the proposed savings 'are unlikely to be matched by efficiency gains within the existing operation'.
The airline said it would now be entering into a consultation period with staff.