Ulster Bank has said it will be looking for 250 more voluntary redundancies, after reporting a loss of more than €9m in the first half of the year.
The bank announced 750 job losses in February with the closure of First Active.
The bank's loan losses jumped to €183m in the first six months.
The results came as its parent bank, Royal Bank of Scotland, reported a net loss of almost £1 billion (€1.16bn) and warned of a poor performance for the next couple of years.
The bank, which has 1.9m customers in Ireland, has also announced a restructuring of its business.
It is getting out of certain significant areas of its business such as loans for development land and certain mortgage products.
The bank says it is taking substantial steps to address the challenges facing the business.
Part of this means 250 more job losses, bringing the total number of job cuts at the bank to 1,000 this year.
Ulster Bank says new opportunities in the Irish economy are limited, it is cautious and careful in terms of its outlook, but that it is very confident about its future as a core part of RBS.
The finance union has said Ulster Bank's plans to seek redundancies is profoundly disappointing.
In a statement, the IBOA said a rationalisation programme involving 750 job losses was not yet completed.