Sixteen people are set to lose their jobs in July when the Connacht Tribune Newspaper Group shuts its printing press.
The printing operation has been in existence in Galway city for almost 100 years and has printed other regional and national newspapers as well as its own publications.
The firm has blamed the closure on an increased demand for full colour newspapers and earlier printing deadlines, which it can no longer meet.
From July the Connacht Tribune will outsource its printing operations.