Almost 75% of US multinationals operating in Ireland said their international colleagues believe the cost of doing business here is too expensive, according to a new survey from the American Chamber of Commerce.
Half of the 55 companies surveyed said it is becoming more difficult to get additional investment from their parent company because of a hike in costs over the past two years.
Three quarters say the cost of doing business is the main factor affecting the development of their business here - with transport, telecom, energy infrastructure, Government policies and European policies other considerations.
However, in the short term the outlook for job creation and investment by US firms remains upbeat with nearly half expecting to create more jobs over the next year and a half.