Reports from Guatemala now say that at least 1,500 people are thought to have died in the aftermath of Hurricane Stan.
The storm hit the region as a hurricane on Tuesday before being downgraded to a tropical storm.
The country's vice-president, Eduardo Staines, said that the full extent of the damage was still unknown as about 90 villages remain cut off.
The towns of Panajab and Tzanchaj, 180km west of Guatemala City, were hit by massive mudslides triggered by the storm.
1,400 people remain missing in Panabaj, after tonnes of mud and debris buried the Mayan village.
Dozens of bodies have already been recovered, but with so many victims feared buried, authorities have said they may abandon the search and declare the village a mass grave.
More than 100 people have been killed in El Salvador, Honduras, Nicaragua and southern Mexico.
Mexico has launched a vaccination drive amid an outbreak of dengue fever in the storm zone.
Torrential rain is still falling across much of the region, making the rescue effort all the more difficult.
The 2005 Atlantic hurricane season, which runs from 1 June to 30 November, has been one of the deadliest and most active on record. Stan was the 10th Atlantic hurricane this year.
Hurricane Katrina, which slammed the US Gulf of Mexico coast on 29 August, ravaged New Orleans and coastal areas of Louisiana, Mississippi and Alabama, killing more than 1,200 people and becoming the deadliest storm to hit the United States since 1928.