Minister for Finance Paschal Donohoe travels to Washington today to attend the annual meetings of the World Bank and International Monetary Fund.
Mr Donohoe will also hold talks with senior members of the Trump administration while in the United States, including the Acting White House Chief of Staff, Mick Mulvaney.
He will also meet senior members of the US Congress on Capitol Hill, such as Chairman of the House Ways and Means Committee Richard Neal, and Chair of the Senate Finance Committee Chuck Grassley.
The discussions will focus on EU-US relations post-Brexit and the economic relationship between the US and Ireland.
During his visit, Mr Donohoe will meet senior members of both the IMF and the World Bank Group, including the new Managing Director of the IMF, Kristalina Georgieva.
In a public address tomorrow to the Brookings Institution in Washington, Minister Donohoe will speak about the challenges posed by Brexit and the future relationship between Ireland, the EU and the UK, and the importance of transatlantic relations.
Speaking ahead of his visit, Mr Donohoe described Ireland and the US as important partners.
"During my visit, I will also take the opportunity to engage with the highest levels of the US Administration, and the many friends of Ireland on Capitol Hill, to discuss the two-way economic and trade relationship which is supporting jobs in both countries, and how we can continue to grow and strengthen this mutually beneficial relationship."