Around 350 Irish-based jobs are under threat at Facebook parent company Meta.
The company employs around 1,800 people in Ireland.
Meta today began notifying staff of how they will be affected by plans to cut 8,000 jobs globally, which is around 10% of its workforce.
Irish-based staff received early morning emails notifying them if they will be potentially impacted by the redundancies.
Meta has submitted a collective redundancy notification to the Department of Enterprise.
The company has not commented on how the cuts will impact its Irish operation, but sources said the timelines and processes of any redundancies will be defined by Irish law and Government guidelines, and that Meta will comply with all its legal requirements.
The job cuts were first reported last month after management issued a memo to staff, which also stated that the company will not fill thousands of open jobs it had been hiring for.
Reuters has reported that today's cuts will be accompanied by a fresh round of organisational changes aimed at improving the company's AI workflows.
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In a memo to staff issued earlier this week, Meta Chief People Officer Janelle Gale told employees the company plans to move 7,000 workers to new initiatives related to AI workflows and to eliminate managerial roles.
The cuts come as Meta increases spending on AI.
Meta CEO Mark Zuckerberg has previously said that 2026 would be the year that AI starts to dramatically change the way the company works, with investments in AI tools that would involve "flattening teams".
"We're starting to see projects that used to require big teams now be accomplished by a single very talented person," Mr Zuckerberg said in January.
In March, it emerged that 15 jobs were under threat at the company's Irish operation linked to the adoption of AI.
Irish-based Meta staff were also impacted by a redundancy announcement in January last year, when the company said it would cut around 5% of its "lowest performing" staff globally.
The company previously cut around 840 jobs in Ireland, with rounds of redundancies in November 2022 and again in May 2023.
'Govt will have your back' - Burke
Minister for Enterprise Peter Burke has said that the Government will support Meta employees.
"My message is very clear to employees in Meta, first of all the Government will have your back. We will support you to gain employment again," he said.
"We have a very vibrant employment market right now, about 2.83 million people employed and particularly in the skill sets that many have in Meta and the IT sector, there is a huge demand in the wider economy the for those skills.
"Any additional training that is needed will be given by the Government.
Watch: Peter Burke says Govt will have the backs of Meta employees
"I acknowledge that it is very distressing when you have an uncertain future, when you get news of this magnitude but the government will work with you to support you and to grow your career path.
"Any support that families who are getting this news will need will be given by the government right across skills and supports which will be critically important.
"IDA Ireland are engaging very closely with Meta over the coming hours and days to ensure that we still remain in a good position in terms of job numbers and it is key that a lot of the engineering function and AI capacity will continue to be built in Ireland," the minister added.
Labour call for strategy to protect jobs
Labour's enterprise spokesperson George Lawlor has called on Mr Burke and Minister of State Niamh Smyth to develop a strategy to protect tech jobs as the contagion of redundancies continues to spread in the sector.
"This is a deeply worrying and stressful time for anyone employed by Meta and I firstly want to express my solidarity with those people working there, their families and their communities," Mr Lawlor said.
"Minister Burke must work with Meta to ensure fairness is applied and to protect jobs and livelihoods where possible. We need to see a comprehensive plan in place for the State to help secure jobs and protect worker’s incomes in the event their employer and sector faces a downturn or a change in business model.
"It is not just workers who are directly employed by these companies which are affected either. The cumulative effect of these cuts are devastating for families and for people who are indirectly employed by the tech industry are too.
"Combined with spiralling food, fuel, energy, and housing prices, and the shameful rental changes that are increasing rents and driving evictions, this is a very worrying time for working people in the sector, and indeed across the country," he added.
The Financial Services Union (FSU), which represents workers in the tech sector, said a dangerous stage is being reached where regulation of AI is trailing implementation.
"Full and transparent stakeholder involvement is required from unions to employers and regulators to legislators to manage the change that AI will make to the workplace and to jobs," an FSU spokesperson said.
"Without that collaboration we will continue to see announcements of job losses like we have seen today," the union added.