The US Special Envoy for Northern Ireland, Mick Mulvaney, will make his first visit as Envoy to Ireland and the UK next week.
Mr Mulvaney will travel to Dublin, Belfast and London.
According to the US State Department, in Belfast, he will meet with representatives of Northern Ireland's devolved government and civil society to discuss the continued implementation of the Good Friday Agreement, as well as current political and economic developments in light of the ongoing coronavirus pandemic and Brexit.
In Dublin, Mr Mulvaney will meet with senior leaders to "advance US policy priorities and affirm the longstanding US commitment to peace and prosperity on the island of Ireland," according to the US State Department statement.
In London, he will meet with members of parliament and government officials to discuss bilateral cooperation to promote Northern Ireland's continued stability and economic development.
"Throughout his travel, Ambassador Mulvaney will highlight strong US support for Northern Ireland, including the prospect of increased trade and investment ties between the United States and Northern Ireland," the US State Department said.
Last week, Mick Mulvaney warned against creating a "hard border by accident" on the island of Ireland following efforts by the UK government to amend parts of the Brexit Withdrawal Agreement.
"The Trump administration, State Department and the US Congress would all be aligned in the desire to see the Good Friday Agreement preserved to see the lack of a border maintained," Mr Mulvaney said in an interview with the Financial Times.
His remarks came days after the Democratic presidential candidate Joe Biden warned that the Good Friday Agreement could not be allowed to become a casualty of Brexit.
"Any trade deal between the US and UK must be contingent upon respect for the Agreement and preventing the return of a hard border. Period." Mr Biden tweeted.
Similar warnings were made by senior Democrats in Congress including the Speaker of the House Nancy Pelosi and the Chairman of the House Ways and Means Committee Congressman Richard Neal.