Tipperary football manager David Power said the "integrity of the league is damaged" after Leitrim conceded a walkover to Down.
On Saturday, Leitrim contacted Down GAA to say they would not be fulfilling their Division 3 fixture in Newry due to a "lack of playing numbers available to travel."
Leitrim's final game is against Tipp this Sunday and they remain hopeful of completing the campaign and giving themselves a chance at staying up.
However, Power questioned whether that game can go ahead.
"I think the whole integrity of the league is damaged after what Leitrim did," he said after watching his own team take a major step towards avoiding the drop with victory over beating Offaly at Semple Stadium.
"There was no mention of how many cases or anything like that. I thought it was very, very poor to be giving a walkover.
"If I was [third-placed] Derry I would be very, very upset as well because not only does it affect the bottom of the league it certainly affected the top of the league. I think there is a lot of people very disappointed in what happened.
"At the end of the day we will be going up to Leitrim but if they are in isolation the rules are 14 days, how are they going to be able to play next weekend?"
In a statement, Leitrim attributed the walkover to "the greater health situation" and aired their hope that they can field a team against Tipp.
Power suggested they could have done more to field a team.
"It is disappointing for that to happen," he added.
"It is after leaving a very, very sour taste in a lot of people's mouths for that to be happening at inter-county level. We're after having many issues over the last couple of weeks. We had close contacts, and lucky enough there were no positive cases.
"But Fermanagh [who lost 10 players due to the coronavirus] as far as I know, went down with 18 men down to Clare [they ultimately had a panel of 26], so are you telling me that Leitrim couldn't get 15 to 20 players to play against Down?"