The family of Archie Battersbee have said they "want something good to come out of this tragedy" as they vowed to call for "change".

The 12-year-old died yesterday in the Royal London Hospital after weeks of legal wrangling.

Archie had been in a coma since he was found unconscious by his mother Hollie Dance at his home in Southend, Essex, south England on 7 April.

He was being kept alive by a combination of medical interventions, including ventilation and drug treatments.

Doctors treating the schoolboy for the last four months declared Archie to be "brain-stem dead", prompting a lengthy but ultimately failed legal battle by his family to continue his life support treatment in the hope he would recover.

In recent days, his parents had made bids to Britain's High Court, Court of Appeal and the European Court of Human Rights to have him transferred to a hospice to die, but these were rejected.

Barts Health NHS Trust had said Archie's condition was too unstable for a transfer and that moving him by ambulance to a different setting "would most likely hasten the premature deterioration the family wish to avoid, even with full intensive care equipment and staff on the journey".

Hollie Dance outside the Royal London Hospital yesterday after Archie died

In a statement, released through the Christian Legal Centre, which has been supporting the family's case, the family said: "Yesterday we lost our beautiful boy, Archie. He has fought against all the odds since April, and we are so proud of him.

"We are thankful for the huge amount of support we've received from so many different people. We are grateful to our legal team and others who have stood with us as we have faced these difficult challenges.

"We want something good to come out of this tragedy and the horrendous experience we have been put through by the system.

"No parent or family must go through this again. We have been forced to fight a relentless legal battle by the Hospital Trust while faced with an unimaginable tragedy.

"There must be an investigation and inquiry through the proper channels on what has happened to Archie, and we will be calling for change."

Ms Dance has previously called for reform through "Charlie's Law".