More than 300,000 video game fans will descend on Cologne for the chance to be among the first to play the latest games, including the new Call Of Duty, when Gamescom begins tomorrow.
The video game trade show differs from fellow industry event E3 in that it is open to the public, with many fans - often in costumes of their favourite characters - able to play upcoming games for the first time.
This year's event is expected to see the next instalment in the Call Of Duty series, Infinite Warfare, showcased.
It is predicted to be popular among visitors as is EA Sports' Fifa 17, the latest in the long running football game franchise.
Both games are due to be released later this year.
Sony's PlayStation VR headset is also likely to be on show, giving many consumers their first look at the system which is set to be released in October and is designed to plug directly into the PlayStation console in order to run
Many rival virtual reality systems currently require a powerful PC to function properly.
However, Sony, Microsoft and Nintendo are unlikely to give more details on their next generation of consoles, all of which are due to be released in the next year.
Microsoft plans Project Scorpio for late 2017, and claim it will be the "world's most powerful console", containing specifications similar to high-end gaming PCs.
Sony's PlayStation Neo is due later this year and is said to support ultra high definition 4K video, but the firm is planning a separate event in September to discuss the system.
While little is known of Nintendo's next console, the NX, reports suggest the Super Mario creator is unlikely to use Gamescom as the platform to finally reveal the device.