The Tuam Home Survivors Network has said inquests must be held into the deaths of all those who died in the Bon Secours run institution.
In a statement , the group - which includes a number of people who were born in the Home, as well as relatives of those who were placed there - says there can be no closure on the issue, until the causes of death in all cases is established.
The Network says that the latest report from the Commission of Investigation into Mother and Baby Homes should have provided greater clarity.
It claims there is no certainty that all children registered as dead did in fact die at the time that deaths were officially registered.
The group has called on the Commission to clarify the basis on which it has come to this conclusion and to provide greater clarity about the documentary evidence in this regard.
The statement says the full horror of what happened at the home in Tuam has not yet been exposed.