Two seriously ill crew members on a cruise ship amid a deadly hantavirus outbreak will be evacuated via Cape Verde to the Netherlands, allowing the vessel to sail on to Spain's Canary Islands, the operator said.
Spain's health ministry said the ship was due to arrive in the Canaries in "three to four days" but did not specify the port.
"Once there, the crew and passengers will be duly examined, cared for, and transferred to their respective countries," it said.
The health ministry said the World Health Organization had explained that the Canary Islands were "the closest place with the necessary capabilities" medically.
The MV Hondius has been at the centre of an international health scare since Saturday, when the WHO was informed that the rare disease - usually spread from infected rodents typically through urine, droppings and saliva - was suspected of being behind the deaths of three of its passengers.
As others fell ill, passengers and crew have been in isolation after Cape Verde authorities barred the ship from docking.
The ship is anchored just off the island nation's capital Praia.
Two Irish people are among the passengers on board the ship.
The Dutch operator Oceanwide Expeditions indicated yesterday that a solution was in sight, with plans to evacuate two sick crew members to the Netherlands for "urgent medical care", along with a third person who had been in close contact with a German passenger who died on Saturday.
The WHO also said medical evacuation plans were under way.
Once the evacuation has taken place, MV Hondius "can continue its route", Ann Lindstrand, the WHO's representative in Cape Verde, said.
Oceanwide Expeditions meanwhile said its plan was for the ship to sail north "to the Canary Islands, either Gran Canaria or Tenerife, which will take three days of sailing".
'Complicated'
The cruise, which set sail from Ushuaia in Argentina on 1 April destined for Cape Verde, counted 88 passengers and 59 crew members, with 23 nationalities onboard, the WHO said.
One of the dead, a Dutch woman, had left the ship at the Atlantic island of Saint Helena and had flown to Johannesburg where she died on 26 April.
Two hantavirus cases have been confirmed - including in one of the fatalities and a British passenger currently in intensive care in Johannesburg - with five further suspected cases, the WHO said.
Three of those seven have died; the one in Johannesburg was critically ill, and three still on board had reported milder symptoms, including one who is now asymptomatic, it said.
The WHO was trying to deduce how hantavirus had appeared on the ship, with the first person who died having developed symptoms on 6 April.
Human-to-human transmission has only been reported in previous outbreaks of one specific hantavirus called Andes virus, which circulates in South America.
WHO epidemic and pandemic preparedness and prevention director Maria Van Kerkhove told reporters the virus species had yet to be confirmed, but highlighted that WHO had been told "there are no rats on board" the ship.
South African researchers were sequencing the data, said Van Kerkhove, who added that "our working assumption is that it is the Andes virus".
"We do believe that there may be some human-to-human transmission that is happening among the really close contacts".
The first two fatalities were a Dutch couple - a man who died on 11 April and his wife who died after she disembarked in Saint Helena to accompany his body.
The wife was suffering from "gastrointestinal symptoms" and "deteriorated" during a flight to Johannesburg on 25 April, the WHO said. She died the following day.
Efforts are under way to trace people on that flight, which South African-based carrier Airlink said was carrying 82 passengers and six crew.
The South African authorities had asked the airline to notify the passengers that they must contact the health department, a representative, Karin Murray said.
Van Kerkhove said the typical incubation period for hantavirus was between one and six weeks, leading the WHO to believe that the Dutch couple, who had been travelling in South America, "were infected off the ship".
Genetic sequencing of virus being carried out
A WHO spokesperson said that it "may take some time to get all the answers" as to how the outbreak occurred.
Speaking on RTÉ's News at One, Tarik Jašarević said genetic sequencing of the virus is being carried out in South Africa to understand what type of hantavirus it is.
"There are a number of people who have been identified to follow up with (from a flight to Saint Helena and Johannesburg) in terms of contact tracing.
"We believe the risk to the wider general public is low, because we know that the hantavirus is normally transmitted through contact with animals.
"If there is a human-to-human transmission, it has to be close contact.
"However, we take this event very seriously, and we are doing everything we can to understand it better to make sure that people on the boat can arrive back safely, Mr Jašarević said.
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The Hondius is carrying mostly British, American and Spanish passengers on a luxury cruise that set off from the southern tip of Argentina in late March.
The cruise visited the Antarctic peninsula and South Georgia and Tristan da Cunha - some of the remotest islands on the planet.
The voyage was marketed as an Antarctic nature expedition, with berth prices ranging from €14,000 to €22,000.
Read more:
Two Irish passengers on board virus-hit cruise ship
Timeline of events on board MV Hondius
What is hantavirus and how deadly is it?
'A lot of uncertainty' - passenger
"We're not just headlines: we're people with families, with lives, with people waiting for us at home," Jake Rosmarin, a US travel blogger, said in a tearful Instagram video post from the ship on Sunday.
"There is a lot of uncertainty and that is the hardest part," he added.
