A "comprehensive investigation" will take place into the death of a 16-year-old girl at University Hospital Limerick this week, UL Hospitals Group has confirmed.

Aoife Johnston, from Shannon in Co Clare, died from meningitis in the hospital on Monday.

In a statement, UL Hospitals group said a Serious Incident Management Team has been established and a comprehensive investigation would take place.

The group said it wished to "extend our sincere condolences to the family following their devastating loss."

Taoiseach Leo Varadkar has said an investigation into Ms Johnston's death should be done thoroughly and as quickly as possible.

Speaking yesterday Mr Varadkar said he was sorry to hear of her death, saying "it's devastating for the family, particularly at this time of year and I want to extend my condolences to her family and friends and of course, to anyone who knew her."

He said it was his understanding that a "serious incident management team has now been established" which will review her treatment.

"It is really important that an investigation is carried out, and that the case is fully reviewed and that we can understand what happened and whether it was preventable or not and what can be done in future to improve the situation," he said.

"I'll certainly seek an assurance from the HSE... that that investigation will be done thoroughly and as quickly as possible because I know that's what the family would expect and that's what they've a right to expect."

Yesterday the HSE's Chief Operating Officer said an investigation had been launched into Ms Johnston's death.

Speaking on RTÉ's Morning Ireland, Damien McCallion offered his sympathies to her family and said that the investigation will work closely with them.

"It's a horrible thing to happen to any family, particularly at this time of year," he said.

He said he did not think it was appropriate to comment any further on the matter at this time.

Earlier this week the Irish Nurses and Midwives Organisation called on management at UHL to prioritise the clinical needs of patients in the emergency department.