A 14-year-old has died after testing positive for Covid-19, the Health Protection Surveillance Centre has reported.
The case is recorded in the latest coronavirus deaths report for the week to 9 November last.
The teenager is the youngest person to die in Ireland with the disease.
Before now, the youngest person to die due to Covid-19 here was 17 and the oldest was 105.
In the past week, 25 people with Covid-19 were recorded as having died during that time period.
Earlier, Health Service Executive Chief Clinical Officer Dr Colm Henry warned that the whole healthcare system is under huge pressure.
It followed the reporting of 3,680 new cases of Covid-19 by the Department of Health.
The number of people in hospital who have tested positive for the disease is 543, down eight since yesterday. Of these, 97 are receiving treatment in intensive care, an increase of eight overnight.
Northern Ireland reported 1,462 new coronavirus infections and six more deaths.
Speaking on RTÉ's Six One, Dr Henry said it was not just about hospitals feeling the strain but "the whole healthcare system, from testing and tracing to GPs - they are all under huge pressure".
While the conversion rate from cases to hospitalisations was much lower than in January due to vaccination, "nevertheless, as cases go up, that will mean more people coming into hospital and needing beds and some will end up in ICU".
Health Service Executive CEO Paul Reid said hospitalisations have increased by 20% in the last week and warned that the health system alone cannot find a way out of the current wave of Covid-19.
Speaking on RTÉ's News at One, he said that "no health system on its own can get its way out of this ... and cope with that level of surge and relentlessness at a peak that we are seeing right now".
Mr Reid said RSV (respiratory syncytial virus) is leading to hospitalisations, while other seasonal viruses are also having an impact, with many emergency departments seeing presentations up 20% on pre-pandemic figures.
He said many attendances are older people impacted by delayed care as a result of the pandemic.
Mr Reid said increased resources have been put in place, with 11,000 extra staff and 900 more hospital beds, but the surge continues to stretch the system.
He said that even the most resourced healthcare systems in Europe are under significant pressure, including in the Netherlands and Germany.
The number of Covid-19 outbreaks in Ireland increased last week, according to the latest figures from the Health Protection Surveillance Centre.
There were 173 outbreaks, an increase of 45 on the previous week.
The number of reported outbreaks rose in private houses, workplaces, residential institutions and hospitals.
However, outbreaks in nursing homes reduced from six to three.
There were 34 private house outbreaks, 24 in the workplace, 20 in residential institutions and ten in hospitals.
While there were 34 outbreaks reported in schools last week, this included 32 outbreaks reported late from May and June.
Mr Reid said the actions people take over the coming weeks will have a significant impact.
"We can turn this around, boosters will help and third vaccines for immunocompromised are helping, but there is a timeframe, particularly over the next few weeks, [where] the actions we take will have a huge benefit," he said.
Mr Reid added that the benefits of booster vaccines are being seen in nursing homes, but there are still outbreaks, although with a smaller numbers of cases and sickness.
He said 4,400 healthcare workers are currently absent due to Covid-19, affecting frontline nursing services.
Mr Reid also said that the move to introduce some automation to the test and trace system has "proven beneficial", with 184,000 lab tests completed since last week, the highest number since the pandemic started.
He said that the HSE has seen "strong support and compliance" in regards to this new automated system.
"We are getting those contacts in. People are uploading their contacts and notifying us of it.
"If you are a positive case, you still get your phone call, you still get your details, and then uploading some contacts, but this is all part of good practice of automation," he said.