Doctors, nurses and pharmacists will administer the Covid-19 vaccines under proposals being drawn up by the Government.
A logistical plan going to Government late tomorrow will detail how various vaccines will be stored and transported.
The plan will be considered by the Cabinet on Tuesday morning.
It will also place an emphasis on developing a well communicated, safe and equitable strategy.
The Government believes communication with health professionals and the public is going to be key to delivering the Covid-19 vaccination programme.
The vaccines will be provided free of charge.
Earlier today, the Government was urged to re-examine its prioritisation list for receiving the Covid-19 vaccine, particularly when it comes to under-18s who have serious underlying health conditions.
Speaking during Leaders' Questions in the Dáil, Social Democrats co-leader Róisín Shortall said their lives were often "desperately hard" but the past year has been "appalling".
She spoke about a 17-year-old girl, with underlying health conditions, whose 19-year-old sister had to move out of the family home due to Covid-19 concerns.
Tánaiste Leo Varadkar said that Ms Shortall had raised a "valid case that needs to be listened to" and he would raise the issue with the Chief Medical Officer the next time they met.
He clarified that the sequencing proposals on vaccine roll-out had not been modified by ministers at last Tuesday's Cabinet meeting but the list could "evolve as new information emerges" - particularly when "new vaccines emerge."
The Tánaiste said the reason that people under 18s with underlying health conditions, and pregnant women, were low down the list was because the risk was deemed to be "very low" by scientists.
He also added that not very many children or pregnant women participated in the vaccine trials, but that didn't mean it wasn't safe for them.
Regarding the publication of the logistical plan to roll-out the vaccines across the country, Mr Varadkar said it was due to be completed tomorrow, but no decision has been taken whether it will be published then or next Tuesday.
He said Taoiseach Micheál Martin was currently in Brussels on EU business, and it might not be possible to organise at Cabinet meeting tomorrow.
If that was the case, the matter might be deferred until the regular Cabinet meeting Tuesday.
Adverse reactions to vaccines 'normal'
Meanwhile, a professor of Molecular Virology at Queen's University Belfast said it is "normal that people have rare reactions to all vaccines".
Professor Ultan Power was speaking after two NHS workers had allergic reactions following their Covid-19 vaccinations with the Pfizer/BioNTech vaccine in the UK.
Prof Power described the advice given by UK authorities, namely not to give the vaccine to people with a history of allergic reaction, as "relatively normal at this stage."
Speaking on RTÉ's Morning Ireland, he said the experience of the two people in the UK "shows the importance of post rollout monitoring of vaccines to make sure that we pick up those rare events that might could preclude somebody from getting the vaccine."
He said the experience of people who have had reactions to the vaccine will be studied to determine the component of the vaccine that caused the reaction.
"This would precipitate studies to try and reformulate the vaccine and to remove part of it that may cause reactions in those individuals", he said.
The president of the epidemiology and public health section of Britain's Royal Society of Medicine has described the relaxation of Covid-19 measures over Christmas as a "recipe for disaster".
Dr Gabriel Scally said there should be no relaxation of measures over Christmas.
Speaking on RTÉ's Today with Claire Byrne, he said "We should be keeping our guard up. Some of the features of Christmas are not helpful with the meeting of multi-generational families over quite a period of time, the weather, masks not being used, and a lot of people coming into the country.
"As a public health doctor, it is a real recipe for disaster come January and February."
Additional reporting Fergal O'Brien, Paul Cunningham
