President Michael D Higgins has said his thoughts and prayers are with those who have lost their lives, and their families, following yesterday's explosion in Creeslough, Co Donegal.
Gardaí confirmed that ten people have died following the blast, which happened at a petrol station in the village around 3.20pm.
In a statement this morning, President Higgins said: "May I, as President, express what I know will be the shock shared by all people throughout the country on learning of the terrible tragedy which has unfolded in Creeslough, Co Donegal.
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"All of our thoughts must go out to all of those who have been affected. Those who have got news of loss of a loved one, those injured and, most of all, those who are waiting with anxiety for news of their loved ones."
President Higgins said the tragedy is a "terrible blow" to a community that is closely knit and where every loss and injury "will be felt by every member of the community and far beyond".
The president paid special tribute to members of the local community and emergency services across the island, who he said reacted swiftly to the scene of the explosion and continued to work through the night.
"All of our best thoughts and prayers go to those who have lost their lives and their families. Ar dheis Dé go raibh a n-anamacha."
Taoiseach Micheál Martin said the incident has been the "darkest of days" for Donegal.
"I wish to express my deepest sympathies to their family, and friends, and to the entire community of Creeslough, on this darkest of days for Donegal and the entire country."
"People across this island will be numbed by the same sense of shock and utter devastation as the people of Creeslough at this tragic loss of life," he said.
"We are witnessing a terrible tragedy on a wonderful community"
— RTÉ News (@rtenews) October 8, 2022
Taoiseach Micheál Martin says the entire nation is mourning for the people of Creeslough this morning, and pays tribute to emergency services for their efforts after the incident | More: https://t.co/CYI0HeHLfo pic.twitter.com/KZVqU4Ozv3
Speaking on RTÉ's Morning Ireland, Mr Martin paid tribute to the emergency services "who went into harm's way and did everything they could" to rescue those trapped.
He said the entire nation is in mourning.
"We're witnessing a terrible, terrible tragedy on a wonderful community in Creeslough, and our thoughts and prayers are with them," he said.
"The entire nation is mourning for the people of Creeslough this morning. I think everybody is shattered by the scale of this. We will ensure that all the services of the state will be there for the people of the community in the days ahead."
"An explosion ripped through a community hub, where people gathered, met and saluted each other," he said.
"It's a very, very dark time."
Tánaiste Leo Varadkar described the explosion as an "unthinkable tragedy".
"On Friday the nation's collective heart stopped when the news broke," he said.
"This unthinkable tragedy happened in a community which we will all be familiar with, to families who were going about their daily lives like we do. This freak accident has left many empty chairs at dinner tables. It is just too hard to fathom.
"Our thoughts and prayers are with those families who have have lost loved ones, those recovering in hospital, the local community, and our emergency service personnel."
Sinn Féin leader Mary Lou McDonald said it is a "devastating loss for a small community".
In a statement, she said there is "shock right across the island and among Irish people everywhere. We are all holding our loved ones a little closer and a little tighter this morning.
"We are thinking of those who went to a petrol station on a Friday afternoon but didn't come home. We are all standing in solidarity with the community in Creeslough in the difficult hours that lie ahead."
Social Democrats co-leader Róisín Shortall said that the entire nation is numbed with shock and grief.
She expressed her thoughts and sympathies with the community in Cresslough and "with those working tirelessly to support them through this unimaginably difficult time."
Multiple people were treated for injuries at Letterkenny University Hospital but it stood down its major emergency standby protocol around 10pm last night.
Manager of Letterkenny Hospital Sean Murphy said yesterday was an "unbelievably tragic and sad day" for the community and county.
He said there were eight people brought to the hospital, one of whom was transferred to a specialist unit in Dublin, while a number of people were also treated at the scene yesterday.
He paid tribute to the work of staff at the hospital, as well as community and care services in the area.
"I'd also like to acknowledge the support we got from members of the public, those we had to ask to leave the hospital and go for treatment in primary care centres," Mr Murphy said.
Donegal TD and Minister for Agriculture Charlie McConalogue said it was a "devastating event" and a "very dark moment for our county".
Speaking on the same programme, Mr McConalogue said last night was a long night for many and a "difficult place to be".
"It's something unfortunately that is going to irrevocably change lives and mark this community for a long, long time," he said.
Sinn Féin TD for Donegal Pearse Doherty said Creeslough is a community that will be "forever changed" by what has happened.
Speaking on the same programme, Mr Doherty said it is a "very close, tightknit" community and everyone will know of someone who was affected.
"The community's just in shock, we're just numb. There's broken hearts all over," he said.
"I think we're all in shock, not just in Creeslough but right across the county of Donegal. You can see the outpouring of emotions from people right across the island.
"As that shock eases there's supports that will be needed ... as we start to deal with the reality of what has happened in this little village of Creeslough and the devastation and trauma that this has caused."
Local priest Fr John Joe Duffy said this is "beyond anything we ever thought we could experience" in any community, adding that there are parents who have been at the scene all night waiting on news of loved ones.
"It's just heartbreaking for our community, and communities beyond who are also affected," he said.
"I'm just so worried for this community as we face what can only be described as a tsunami of grief."
