Dolly, the world's first cloned mammal, has died. She was six.
The world famous sheep was given a lethal injection after vets discovered she was suffering from a progressive lung disease.
A post-mortem is being done and the Roslin Institute said it would report any significant findings.
The birth of Dolly in July 1996 made headlines around the world and sparked criticisms and fears that human cloning would not be far off.
Scientists defended the creation of Dolly and said the research could help to produce new treatments for many diseases.
Late last year Clonaid, a company founded by the Raelian movement that believes mankind was created by extraterrestrials, announced the birth of the first human clone. But scientists doubt the claim which has never been verified with independent DNA tests.