Le'Veon Bell's one-yard scoring run with no time remaining lifted the Pittsburgh Steelers past the San Diego Chargers 24-20 Monday night.
The Chargers grabbed the lead on rookie Josh Lambo's 54-yard field goal with 2:56 to play. The Steelers then drove 80 yards in 12 plays for the win.
Cincinnati Bengals staged a sensational fourth-quarter comeback to beat the Seattle Seahawks 27-24 in overtime.
Led by quarterback Andy Dalton, the Bengals overturned a 24-7 deficit to keep Cincinnati undefeated and at 5-0 for the first time since 1988 - the last time they went to the Super Bowl.
Dalton threw for a touchdown, ran for another and led the Bengals on a 69-yard drive without a time-out before Mike Nugent tied it with a 31-yard field goal with the final play of regulation time.
Nugent kicked again from 42 yards with 3:36 left in overtime, the ball deflecting off the left upright before going through.
The Buffalo Bills also fought back to win 14-13 as the Tennessee Titans blew a second straight double-digit lead at home. Stephon Gilmore intercepted Marcus Mariota's pass with 1:32 left to seal the win.
Aaron Rodgers threw for two touchdowns and 241 yards as the Green Bay Packers held off the St Louis Rams for a 24-10 victory, while the Philadelphia Eagles ended a three-game losing run at home as they beat the New Orleans Saints 39-17.
Doug Martin was the star, running for 123 yards and scoring three touchdowns as the Tampa Bay Buccaneers beat the Jacksonville Jaguars 38-31 to halt an 11-game losing home run that dated back almost two years.
Robert Alford returned an interception 59 yards for a touchdown as the Atlanta Falcons won 25-19 in overtime against Washington Redskins to remain undefeated.
Two fourth-quarter touchdowns from Jay Cutler led the Chicago Bears to an 18-17 victory over the Kansas City Chiefs and Travis Coons kicked a 32-yard field goal in overtime as the Cleveland Browns snatched a 33-30 win over the Baltimore Ravens.
Tom Brady threw two touchdowns as the New England Patriots blew Dallas Cowboys away in a 30-6 victory to give them a seventh straight win.
Elsewhere, Denver Broncos beat Oakland Raiders 16-10, Arizona Cardinals made light work of Detroit Lions 42-17 and New York Giants scored a touchdown with 21 seconds of the match remaining to beat San Francisco 30-27.