Ireland head coach Andy Farrell has included Connacht's Mack Hansen and Ulster's Mike Lowry in his 37-man squad for the opening rounds of the Six Nations.
The pair are the only uncapped players in the group, while Leinster wing James Lowe misses out due to a muscle injury which will sideline him for a number of weeks.
Uncapped Hansen and Lowry have both trained with Ireland in the past year with Lowry having been involved with the group in the summer of 2021, and Hansen spending a week in camp last November.
Connacht flanker Cian Prendergast has also been named as a development player, with the 21-year-old set to be involved in Ireland's training camp in Portugal later this month.
There is also a recall for second row Kieran Treadwell, who won the last of his three Irish caps in 2017. The Ulster lock replaces Ultan Dillane, who is left out of the squad following confirmation of his move abroad at the end of the season.
Jack Carty joins Johnny Sexton and Joey Carbery among the out-halves, with the Connacht 10 looking to earn his first cap since the 2019 World Cup.
Andy Farrell and the Ireland coaching group have named a 37 player squad ahead of the 2022 Guinness Six Nations Championships which commence in early February.
The squad will be captained by Johnny Sexton who earned his 100th cap for his country against Japan during the November international window.
Ireland will host Wales, Italy and Scotland at the Aviva Stadium over the course of the Championship while also travelling to Paris and London to face France and England respectively.
"In November we challenged the group to get up to speed quickly so that the team could perform at international level. The same will apply for this Six Nations campaign, we need to be at our best against Wales on the opening weekend," said head coach Andy Farrell.
"We have a strong squad with competition for places across the board, there is a nice blend of experienced internationals and guys who have had their first taste of this level in the past 12 months. The games in November gave us a good foundation to build on and areas where we know we will have to improve.
"It will be an exciting Championship with so many strong squads and impressive performances across the board during the autumn."
Ireland's opening fixture of the 2022 Six Nations Championship is against Wales on Saturday 5 February (LIVE on RTÉ2)
IRELAND Guinness Six Nations Squad 2022
Backs (17)
Bundee Aki (Connacht/Galwegians) 33 caps
Robert Baloucoune (Ulster/Enniskillen) 2 caps
Joey Carbery (Munster/Clontarf) 27 caps
Jack Carty (Buccaneers/Connacht) 10 caps
Craig Casey (Munster/Shannon) 4 caps
Andrew Conway (Munster/Garryowen) 27 caps
Keith Earls (Munster/Young Munster) 96 caps
Jamison Gibson Park (Leinster) 12 caps
Mack Hansen (Connacht) uncapped
Robbie Henshaw (Leinster/Buccaneers) 53 caps
James Hume (Ulster/Banbridge) 1 cap
Hugo Keenan (Leinster/UCD) 16 caps
Jordan Larmour (Leinster/St Mary's College) 30 caps
Michael Lowry (Ulster/Banbridge) uncapped
Conor Murray (Munster/Garryowen) 92 caps
Garry Ringrose (Leinster/UCD) 37 caps
Johnny Sexton (Leinster/St Mary’s College) 101 caps CAPTAIN
Forwards (20)
Ryan Baird (Leinster/Dublin University) 6 caps
Finlay Bealham (Connacht/Buccaneers) 18 caps
Tadhg Beirne (Munster/Lansdowne) 25 caps
Jack Conan (Leinster/Old Belvedere) 22 caps
Gavin Coombes (Munster/Young Munster) 2 caps
Caelan Doris (Leinster/St Mary’s College) 12 caps
Tadhg Furlong (Leinster/Clontarf) 52 caps
Cian Healy (Leinster/Clontarf) 112 caps
Iain Henderson (Ulster/Academy) 65 caps
Rob Herring (Ulster/Ballynahinch) 23 caps
Ronan Kelleher (Leinster/Lansdowne) 16 caps
Dave Kilcoyne (Munster/UL Bohemians) 45 caps
Peter O’Mahony (Munster/Cork Constitution) 79 caps
Tom O’Toole (Ulster/Ballynahinch) 2 caps
Andrew Porter (Leinster/UCD) 40 caps
James Ryan (Leinster/UCD) 40 caps
Dan Sheehan (Leinster/Lansdowne) 2 caps
Nick Timoney (Ulster/Banbridge) 2 caps
Kieran Treadwell (Ulster/Ballymena) 3 caps
Josh van der Flier (Leinster/UCD) 35 caps
Development Player
Cian Prendergast (Connacht)
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