Live blog on RTÉ Sport Online and the RTÉ News app from 2pm, Saturday.
Live updates on RTÉ Radio 1's Saturday Sport.
Live coverage on RTÉ One for the 3pm kick-off, highlights on Against the Head, RTÉ2, Monday 8pm.
On Saturday morning, rain affecting eastern and southern counties will ease and clear leaving a fresh and blustery day nationwide with sunny spells and scattered showers. Maximum afternoon temperatures of 8 to 11 degrees in fresh west or southwest winds.
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STATE OF PLAY
Ireland kicked off the inaugural Autumn Nations Cup with a comfortable win over a Wales side that struggled to muster a challenge, running out 32-9 winners at the Aviva Stadium.
But England went one better by gaining the extra bonus point in their win over Georgia as they coasted to a 40-0 win at Twickenham.
With Wales at a relatively low ebb, Saturday's clash between Ireland and England is likely to decide which nation finishes top of Group A.
An Irish victory on English soil would all but seal a fixture against the top side in Group B, given that tournament invitees Georgia would be the last remaining hurdle in Dublin in a week's time.
However, England have definitely had the upper hand in the arm wrestle between the sides in recent meetings and will go in as favourites especially when the team news is taken into account.
The Wales game saw Ireland blood more debutants, with James Lowe the most notable new face as the New Zealand-born Leinster wing made a favourable impression which was capped off with a late try.
Ulster's Billy Burns also made his debut at out-half as a substitute but was withdrawn later on in the match due to a head injury.
While Lowe retains his place in the starting team for a second week, Burns has also recovered in time to resume his place on the bench against the nation of his birth.
However, last Friday's fixture did come at a cost on the injury front with Ireland captain Johnny Sexton, who Burns came on for in Dublin, forced off with a hamstring strain that keeps him out for the Twickenham test.
Ross Byrne is tasked with the challenge of playmaking against England in an inexperienced half-back partnership - in international test terms - with Jamison Gibson-Park.
Robbie Henshaw, who suffered an abductor strain, is replaced in the centre by Bundee Aki who slots in beside Chris Farrell, while second row Iain Henderson, an absentee against the Welsh, returns to take his place among the options on the bench.
Henderson's Ulster team-mate Jacob Stockdale also returns to join him among the replacements.
Keith Earls and CJ Stander go straight back into the Ireland wing and back row respectively in place of Andrew Conway and Josh van der Flier respectively.
And while the front five sees no changes, there is one significant promotion in the sense of James Ryan - oft cited as a potential future Ireland captain - skippering the side in Sexton's absence.
England, meanwhile, are not taking the visitors lightly with Eddie Jones saying he has "picked the strongest team possible" with a host of experienced names selected.
George Ford returns to take a place on the English bench after recovering from an Achilles injury.
Ireland: Hugo Keenan, Keith Earls, Chris Farrell, Bundee Aki, James Lowe, Ross Byrne, Jamison Gibson-Park; Cian Healy, Ronan Kelleher, Andrew Porter, Quinn Roux, James Ryan (capt), CJ Stander, Peter O'Mahony, Caelan Doris.
Replacements: Rob Herring, Ed Byrne, Finlay Bealham, Iain Henderson, Will Connors, Conor Murray, Billy Burns, Jacob Stockdale.
England: Elliot Daly; Jonathan Joseph, Ollie Lawrence, Henry Slade, Jonny May; Owen Farrell (capt), Ben Youngs; Mako Vunipola, Jamie George, Kyle Sinckler, Maro Itoje, Joe Launchbury, Tom Curry, Sam Underhill, Billy Vunipola.
Replacements: Tom Dunn, Ellis Genge, Will Stuart, Jonny Hill, Ben Earl, Dan Robson, George Ford, Max Malins.
Referee: Pascal Gauzere (France)
Assistant Referee 1: Mathieu Raynal
Assistant Referee 2: Alex Ruiz
TMO: Nigel Owens
WHAT THEY SAID
Andy Farrell (Ireland head coach): "You can't make promises. I've not got a crystal ball. But what I do know is that this is a different group and it's a different game at the weekend.
"We've got new combinations all over the field that are coming together and learning from these type of experiences all the time.
"They've trained well, prepared well and they can't wait to get out there and show what they can do.
Eddie Jones (England head coach): "I heard someone calling [the Ireland team] the United Nations, so I had a little chuckle.
"Andy Farrell, Mike Catt and Simon Easterby are just selecting the team they are allowed under the regulations.
"I can understand how Irish people would be upset about Irish-born players missing out, but they are the laws and regulations of international rugby. They are just sticking by the regulations."
Follow England v Ireland this Saturday via our live blog on RTÉ.ie/sport and the RTÉ News app, watch live on RTÉ One from 2pm, or listen to live updates on RTÉ Radio 1's Saturday Sport.
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