Cian Healy has been ruled out of Ireland's remaining Six Nations games because of the hip injury suffered against England.
The loosehead prop was forced off after 26 minutes of the 24-12 defeat at Twickenham, having been hurt in a ruck during the lead-up to Elliot Daly's try.
Ireland head coach Andy Farrell wasn’t optimistic about Healy’s condition during his post-match press conference and scans have confirmed he faces a spell on the sidelines.
Healy’s injury will open the door for Dave Kilcoyne, who replaced him at Twickenham. He has won 39 caps for Ireland, but only eight have been as starts.
Elsewhere, Ireland have released six players back to their provinces for next weekend’s Pro 14 fixtures.
Will Connors, Max Deegan, Dave Kearney and Luke McGrath will return to Leinster ahead of Friday’s game against the Ospreys at the RDS, while Munster welcome back Chris Farrell and Jack O’Donoghue for their home game against the Scarlets on Saturday.
Iain Henderson has rejoined the squad for this week’s two-day camp in Dublin, having missed the England game due to the birth of his son.
His Ulster team-mates Billy Burns, Stuart McCloskey, Jack McGrath and Tom O’Toole will also attend the Ireland camp following the postponement of their game against Benetton.
Will Addison remains with Ulster as he continues his rehab from a calf injury.
Ireland squad
Backs: Bundee Aki, Billy Burns, Ross Byrne, Andrew Conway, John Cooney, Keith Earls, Robbie Henshaw, Jordan Larmour, Stuart McCloskey, Conor Murray, Johnny Sexton, Jacob Stockdale.
Forwards: Ultan Dillane, Caelan Doris, Tadhg Furlong, Dave Heffernan, Iain Henderson, Rob Herring, Ronan Kelleher, Dave Kilcoyne, Jack McGrath, Peter O'Mahony, Tom O’Toole, Andrew Porter, James Ryan, CJ Stander, Devin Toner, Josh van der Flier.
