Peter O'Mahony returns to the Munster team for Saturday's Guinness Pro14 clash with Ulster at Thomond Park (5.15pm).
The flanker is among eight of Ireland's World Cup squad who may feature for the hosts.
Andrew Conway, Chris Farrell, Niall Scannell, John Ryan, Jean Kleyn, O'Mahony and CJ Stander all start with Conor Murray among the replacements.
JJ Hanrahan, Alby Mathewson and Chris Cloete keep their places in the side after helping Munster to a bonus-point win away to Cardiff Blues last week as Munster make 12 changes.
Academy winger Liam Coombes makes his second Munster start with Mike Haley and Conway completing the back three.
Mathewson and Hanrahan continue their half-back partnership with Rory Scannell and Farrell in the centres.
James Cronin, Scannell and Ryan pack down in the front row with Kleyn and Billy Holland in the engine room.
O'Mahony, Cloete and Stander are named in the back row.
Meanwhile, Ulster make seven changes from the side that defeated Zebre last Friday with Irish internationals Jacob Stockdale and Jordi Murphy making their first appearances this season.
Stuart McCloskey is re-called to join last week's man of the match Luke Marshall in midfield. Angus Curtis will make his first start for Ulster this season at fly-half and is joined by John Cooney
Among four changes in the forwards, Marty Moore returns to make his first start of the season at tighthead, joining Jack McGrath at loosehead and captain Rob Herring to make up an all-international front row.
Sam Carter comes back in to join Alan O'Connor in the second row.
Munster: Mike Haley, Andrew Conway, Chris Farrell, Rory Scannell, Liam Coombes, JJ Hanrahan, Alby Mathewson; James Cronin, Niall Scannell, John Ryan, Jean Kleyn, Billy Holland, Peter O'Mahony (capt), Chris Cloete, CJ Stander.
Replacements: Jeremy Loughman, Kevin O'Byrne, Stephen Archer, Fineen Wycherley, Jack O’Donoghue, Conor Murray, Tyler Bleyendaal, Arno Botha.
Ulster: Matt Faddes, Rob Lyttle, Luke Marshall, Stuart McCloskey, Jacob Stockdale, Angus Curtis, John Cooney; Jack McGrath, Rob Herring (capt), Marty Moore, Alan O'Connor, Sam Carter, Sean Reidy, Jordi Murphy, Nick Timoney.
Replacements: Adam McBurney, Eric O’Sullivan, Tom O’Toole, Kieran Treadwell, Matthew Rea, David Shanahan, Bill Johnston, Robert Baloucoune.