No matches will take place in Laois, Offaly and Kildare for the next two weeks after the National Public Health Emergency Team (NPHET) recommended a partial shutdown in the three counties from midnight.
The restrictions will mostly affect Gaelic games and soccer with both sports back in full swing on the club front.
Horse racing meetings can proceed behind closed doors.
Non-contact sport and training can continue subject to a maximum of 15 people.
In a joint statement between the GAA, the Camogie Association, and the LGFA, it was confirmed that the "suspension on activities covers all collective training, matches, in-person meetings and camps."
The statement went on to confirm that all GAA grounds in the affected counties will remain closed until further notice, with a meeting of the advisory committee on Monday to issue more advice for the clubs.
The FAI similarly advised its clubs that, "this suspension includes all matches and organised training" in the three counties.
We are working with Sport Ireland to confirm details for counties Kildare, Laois and Offaly from tomorrow morning. We will be in touch with clubs as soon as possible this evening. @IrishLadiesGolf @CGI_Golf— Golfing Union of Ireland (@GUIGolf) August 7, 2020
There were four games in the Kildare SHC and four in the Offaly SFC fixed for this weekend, along with a large number of matches at age grade and junior levels in the three counties.
The Kildare and District Underage League has multiple soccer fixtures, from Under-7 to Under-17, listed over the next week but they have now been cancelled.
Laois GAA County Board chairman Peter O'Neill told Drivetime on RTÉ Radio 1 that he felt the county was "targeted", but they had taken the decision to postpone fixtures this evening, even though the restrictions don't come in until midnight.
"We are very disappointed, we had our senior fixtures last weekend and we had a round of fixtures tonight, which we have pulled. The news was very late, at 6 o'clock, to allow us to do that.
"We know it was closing at 12, but we felt it appropriate to pull our fixtures for tonight," said O'Neill.
"The GAA have worked very, very hard in Laois and the clubs of Laois, and it is very disappointing that we have been targeted here as a county with all of these cases have beginning clusters from outside of the county."
There were a number of cases connected to clubs in Laois, but O'Neill said those cases came from outside the county and originated in meat factories.
"We did [have cases] but it was not through the GAA, it came from the meat factories in Kildare. I think that is where the case originated.
"The most important thing is the people's health and we have have abided by the guidelines the whole way throughout... I know the clubs of Laois have been complying completely with that.
"We will continue to abide by the government guidelines. It is sport and I know there are people's lives, at the minute, with business and that, which are going to be affected. We will comply and we will get over it and we will get over more again."