Mickey Harte has made 15 changes from the side that beat Cork in Croke Park, while Jim Gavin has included Diarmuid Connolly in a much-changed Dublin squad for their final Super 8s game in Omagh tomorrow.
While Tyrone bring Padraig Hampsey and Tiernan McCann into their side, the selection of effectively a second string side for their Group 2 decider against the All-Ireland champions highlights the flaws of the Super 8s system.
Ahead of their Healy Park showdown both of last year's All-Ireland finalists have already qualified for the semi-finals after beating Cork and Roscommon and, as they play on Sunday, they will know who lies in wait in the last four after Saturday's Group 2 matches.
Harte will be reluctant to show his full hand to Gavin's five-in-a-row chasing Dubs or risk injuries to key men, while it may also be a factor that the winning team will have a shorter turnaround ahead of a Saturday semi-final.
Connolly's inclusion within the matchday squad will garner attention, but Gavin has made wholesale changes to the team that beat Roscommon.
He has drafted in eight fresh faces - Rory O'Carroll, Davy Byrne, Robert McDaid and Eoin Murchan in defence, plus Eoin O'Gara, Kevin McManamon, Cormac Costello and Eric Lowndes in attack.
These are the final games of the second year of a three-year Super 8s trial and, with Roscommon and Cork reduced to a glorified challenge match, questions will be asked about the viability of the quarter-final format.
Tyrone: Benny Gallen; Ciarán McLaughlin, Pádraig Hampsey, Liam Rafferty; Tiernan McCann, Aidan McCrory, Michael Cassidy; Ben McDonnell, Declan McClure; Richard Donnelly, Kyle Coney, Conan Grugan; David Mulgrew, Connor McAliskey, Conall McCann.
Dublin: Stephen Cluxton; Rory O'Carroll, Davy Byrne, Philly McMahon; Eoin Murchan, Jonny Cooper, Robert McDaid; Brian Fenton, James McCarthy; Eric Lowndes, Cormac Costello, Brian Howard; Kevin McManamon, Eoghan O’Gara, Con O’Callaghan.
Follow Tyrone v Dublin via our live blog on RTÉ.ie/sport and the News Now app, listen to live radio commentary on RTÉ Radio 1 and Raidió na Gaeltachta, or watch live on the RTÉ2.
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