Eight teams will exit the championship this weekend - but eight more will be a step closer to reaching the All-Ireland quarter-final phase come the middle of July.
Remember all games must be decided on the day: if teams are level after 70 minutes there will be two periods of ten minutes extra-time, followed by two more of five if necessary, and, finally, a penalty-taking competition.
SATURDAY 22 JUNE
All-Ireland SFC Qualifiers Round 2
Antrim v Kildare, Corrigan Park, 3pm
Derry v Laois, Owenbeg, 5pm
Longford v Tyrone, Glennon Brothers Pearse Park, 5pm
Leitrim v Clare, Avantcard Páirc Seán MacDiarmada, 6pm
Westmeath v Limerick, TEG Cusack Park, 6pm
Down v Mayo, Páirc Esler, 7pm
Monaghan v Armagh, Clones, 7pm
SUNDAY 23 JUNE
All-Ireland SFC Qualifier Round 2
Offaly v Sligo, O'Connor Park, 2pm
Live blog on RTÉ.ie and the RTÉ News Now App from 2.30pm on Saturday and from 1.30pm on Sunday.
Saturday Sport from 2.45pm on RTÉ Radio 1 will have live updates on all games, with commentary from Pauric Lodge and Martin McHugh on Monaghan v Armagh, and Adrian Eames and Ciarán Whelan on Down v Mayo. John Kenny will provide live Offaly v Sligo updates on Sunday Sport, RTÉ Radio 1 from 2pm
Highlights of all the weekend's action on The Sunday Game and the RTÉ Player from 9.30pm on RTÉ2.
It looks set to be mostly dry on Saturday, with spells of hazy sunshine. Highest temperatures of 17 to 20 degrees in moderate southeast winds.
On Sunday the rain in the southwest will gradually spread to other parts. The best of any dry, bright weather is likely in the north and east of the country in the first half of the day. Highest temperatures of 16 to 20 degrees, in moderate easterly winds. For more go to met.ie
Redemption road begins for some leading lights
Seventy minutes of football can alter one's opinion. Tyrone, we thought, were in the front rank to really put it up to the Dubs further down the line. Donegal, on the basis of their dismantling of the Red Hand a fortnight ago, would now appear to occupy the position.
Mickey Harte's troops are well used to going down the qualifier route and have emerged from it on seven occasions. And while you couldn't say with great certainty that they will escape again, given that a few other big fish are circling the waters, they will know that their first-half performance against Donegal would leave them short against those at the top table.
At times, they were clueless in the efforts to make inroads against the Donegal rearguard, and a change in emphasis away from the running game that got them to an All-Ireland final last season, also seems to have blunted their threat.
The loss of Mark Bradley, Lee Brennan, Ronan O'Neill, who were all effective when sprung from the bench in 2018, is just another reason why Tyrone may not have depth to take them to August.
Longford have produced more than a few shocks through the backdoor, as Mayo, Monaghan and Derry will also testify. They got their show back on the road against Carlow, but it's hard to read too much into that game given how poor Turlough O'Brien's side have been this summer.
And so to Mayo.
My colleague Peter Sweeney has given us a rundown of their recent summer journeys, while also equating it to a certain ITV show that many watch in their droves.
I'm sure many in Mayo are scratching their heads as to how they lost to Roscommon in the Connacht semi, in spite of them dominating much of the possession and having the Rossies in a panic over their kickouts.
Kicking too many wides did not help the Green and Red cause in Castlebar, while Rob Hennelly's performance between the sticks should be grounds for concern. Will David Clarke get a recall? What about Micheál Schlingermann? If Hennelly gets the nod, should his restarts be short
The loss of midfielder Matthew Ruane is a blow after the Breaffy clubman broke his collarbone in an A v B training game last week. Better news, however, is that James Carr may have recovered from the injury picked up against the Rossies, while Cillian O'Connor is set to feature at some stage in Newry after his lengthy lay-off.
Down were pushed hard to get past Tipperary in the opening round and you'll expect Paddy Tally to come up with a defensive plan to keep things tight for as long as possible.
That said, you'd expect Mayo's physical presence and all-round footballing ability to prevail here, as Horan and co strive to get the show back on the road.
It's the first championship meeting between the sides since the 2012 All-Ireland quarter-final which Mayo won by 3-18 to 2-09.
In Clones, Monaghan welcome Armagh in a clash where defeat could spell the end of Malachy O'Rourke and Kieran McGeeney's time in charge of their respective.
Let's be honest, apart from their opening day victory against Dublin in the league, the Farney have yet to fire this year.
They scored a nervy 1-10 to 1-06 win over Fermanagh to reach the stage but they had to work hard to finally dispose of the challenge of a stubborn and dogged Ernesiders who battled to the very end with 12 men.
That said, giving away a needless goal at the death did not help their cause.
Darren Hughes has had an eight-week ban upheld by Central Competitions Control Committee over an infraction during the defeat of Fermanagh.
Hughes, on the comeback trail from a broken ankle, got involved in an altercation with Fermanagh players.
The Monaghan star was a team official on the day.
He remains injured but could return later in the Championship and it is likely he will take his appeal further.
I'm sure the disappointment is still lingering for Armagh fans that they did not seal the deal against Cavan the first day out. Indeed, had they taken two golden goal chances inside the first five minutes in the replay, they may very well now be looking forward to an Ulster final.
If McGeeney's men can jump this hurdle, they could have a lengthy summer in front of them if favourable draws come their way.
Other Super 8s possibles?
Can Kildare get their again? Ok, the Dubs gave them a trimming as expected, but the jury is out, particularly from within, as to whether they get to business end again. They should have enough to account for Antrim.
The Saffron GAA board recently confirmed Corrigan Park in West Belfast as the venue for the game.
The ground belongs to the St John's Club and only hosts 2,000 spectators, but it was passed suitable by safety inspectors to host the Lilywhites.
Derry have form through the backdoor and 2019 was always going to be about rising from the depths for them. Promotion from Division 4 was the precursor to a decent showing in the Ulster opener against Tyrone.
They then made light work of Wexford a fortnight ago and will fancy themselves against a Laois side who are well-beaten docket at the end against Meath.
Derry and Laois have met three times in the qualifiers, with the former winning two of those games in 2001 and 2007.
Westmeath play host to Limerick in Mullingar. The Lake County's win over Waterford was their first in the qualifiers since 2012.
Leitrim made Round 3 last year, but will have to improve on their showing against Wicklow if they are to overcome a Clare side who were more than doughty when going down to Kerry.
It's a first meeting of the sides in the championship.
John Maughan and his management team Kevin Guing and Gerry O'Malley have named their side to take on @sligogaa in the 2nd round of the All Ireland Qualifiers— Official Offaly GAA (@Offaly_GAA) June 20, 2019
Calling all Faithful Supporters to @BordnaMona O'Connor Park on Sunday 23rd June at 2pm #GAABelong #wearethefaithful pic.twitter.com/fZLZHmpDcw
Sligo have yet to win a competitive game this year and travel to Tullamore to take on John Maughan's Offaly.
The latter have shown enough so far to suggest they'll get another day out.