Long-serving Mayo midfielder Seamus O’Shea looks set to miss the rest of the National Football League with an ankle injury.

The 31-year-old is understood to have sustained significant ankle ligament damage during a Mayo training session last week, and was not included in James Horan’s match-day squad for last weekend’s defeat to Galway.

It’s believed that the Breaffy clubman won’t be available for Mayo’s remaining games away to Kerry on Saturday week next or at home to Monaghan on Sunday, 24 March.

He would also miss the League Final were Mayo to qualify for the decider for the first time since 2012.

This injury setback means that O’Shea’s next competitive outing for Mayo could be their Connacht championship opener against New York on Sunday, 5 May at Gaelic Park.

O’Shea has played less than 30 minutes of football for Mayo this year. He came on at half-time during the recent league defeat to Dublin at Croke Park but spent ten minutes in the sin-bin after being shown a black card by referee Barry Cassidy.

Meanwhile, Ger Cafferkey (hamstring), Paddy Durcan (quad) and  Ciaran Treacy (ankle) also missed last Saturday night’s clash with Galway due to their respective injuries.

Cafferkey and Durcan are both expected to be back in the frame for a place in the Mayo panel that travels to Kerry for round six, while Evan Regan (shoulder) and Cillian O’Connor (knee) could also feature.

O’Connor has been rehabilitating from knee surgery since before Christmas, but may be ready to return to play for Mayo’s final two regulation league games.

However, Cian Hanley, who had a similar procedure carried out on his knee in December, revealed last weekend that he would not be ready to return to action before the end of the National League.

Tom Parsons, who has been sidelined since suffering a serious leg injury last May, is continuing his rehabilitation programme and is said to be ‘making good progress’, according to James Horan.