Belgium picked uncapped defender Christian Kabasele ahead of the injured Dedryck Boyata as they named their 23-man squad for Euro 2016.
They have a wealth of attacking talent, including Eden Hazard and Kevin De Bruyne, but are struggling at the back without Boyata, captain Vincent Kompany, Nicolas Lombaerts and Bjorn Engels.
Kabasele, 25, has been a regular at Racing Genk for the past two seasons.
There is a total of 11 Premier League players in Marc Wilmots' line-up, with Hazard and De Bruyne joined by Chelsea goalkeeper Thibaut Courtois, Everton frontman Romelu Lukaku and Liverpool trio Christian Benteke, Divock Origi and Simon Mignolet.
Belgium play friendlies against Finland tomorrow and Norway on Sunday before facing Italy in their Euro 2016 opener in France on 13 June.
The Red Devils then take on Ireland on 22 June before finishing their Group E fixtures against Sweden.
Wilmots said he would rest defender Thomas Meunier, midfielders Mousa Dembele and Radja Nainggolan and Champions League final goalscorer Yannick Carrasco against the Finns.
Belgium Squad:
Goalkeepers: Thibaut Courtois, Jean-Francois Gillett, Simon Mignolet
Defenders: Toby Alderweireld, Laurent Ciman. Jason Denayer, Christian Kabasele, Jordan Lukaku, Thomas Meunier, Thomas Vermaelen, Jan Vertonghen
Midfielders: Mousa Dembele, Marouane Fellaini, Radja Nainggolan, Axel Witsel
Forwards: Michy Batshauyi, Christian Benteke, Yannick Carrasco, Kevin de Bruyne, Eden Hazard, Romelu Lukaku, Dries Mertens, Divock Origi.
