Danish Prime Minister Mette Frederiksen will discuss Greenland with US officials, including Secretary of State Marco Rubio, on the sidelines of the Munich Security Conference, she told reporters.
"We have agreed to hold several meetings with American politicians, including the secretary of state, also (about) Greenland," Danish news agency Ritzau quoted her as saying.
She was speaking when she arrived at the conference, referring to US President Donald Trump's designs on the strategically located and mineral rich Arctic island.
Ms Frederiksen's office told AFP the prime minister would take part in the talks but declined to say whether other members of her government would attend.
The Danish foreign and defence ministers are also attending the Munich Security Conference, which runs until Sunday in the German city.
Since returning to the White House last year, President Trump has argued the US needs to control Greenland - a Danish territory - for security reasons.
Last month, he backed down from his threats to seize Greenland after striking a "framework" deal with NATO Secretary General Mark Rutte to ensure greater US influence.
A US-Denmark-Greenland working group has been established to discuss Washington's security concerns in the Arctic but details have not been made public.
At the same time, the Danish defence ministry said NATO has launched a mission in the Arctic in which Denmark is participating, notably by providing F-35 fighter jets.
In Munich, Ms Frederiksen reiterated her call for Europe to increase its defence at a time when the US is disengaging.
"The Americans have been very honest - from Trump's inauguration speech to a new security strategy and a new defence strategy, the threats against Greenland - everything points in one direction, namely that the US, unfortunately, is moving away" from Europe, she said.
The US secretary of state will attend the conference amid the breakdown in trust between the US and European capitals in the wake of the Greenland matter.
Mr Rubio aims to keep up pressure on Europe, though the tone is expected to be less confrontational than last year.
Last year, US Vice President JD Vance criticised European policies on immigration, populist parties and free speech, saying that freedom of expression was "in retreat" across the continent.
But this year, the vice president - who just finished a visit to Armenia and Azerbaijan - is staying home.
Mr Rubio will lead the US delegation to the annual security and defence talks.
But even if Mr Rubio is more diplomatic than Mr Vance, the United States nevertheless intends to push its European allies, who are still reeling from the political crisis over Mr Trump's demands to acquire Greenland.
"We live in a new era in geopolitics and it's going to require all of us to sort of re-examine what that looks like and what our role is going to be," Mr Rubio told reporters before boarding his plane.
Since returning to the White House in January last year, Mr Trump - who has said the European Union was created to "screw" the United States - has had the continent in his sights.
In his new National Security Strategy, published in December, Mr Trump criticised Europe as an over-regulated continent lacking in "self-confidence" and facing "civilisational erasure" due to immigration.
In Munich today and tomorrow, Mr Rubio is expected to keep pushing Europe to share the burden, especially on matters of common defence.
For Philip Gordon, an expert at the Brookings Institution think tank and veteran of former Democratic administrations, Mr Trump "doesn't see a unified Europe as a partner of the United States, but a threat to the United States".
"The more unified it is, the more he doesn't like it," Mr Gordon said.
A poll conducted by Politico showed that more than 50% of German respondents do not see the United States as a "reliable" ally.
Besides Greenland, the agenda will also include the durability of transatlantic unity, the US security umbrella and the war in Ukraine - as well as ties with Moscow.
French President Emmanuel Macron, who is making the trip to Germany, has said he hopes for a resumption of talks with Russia's Vladimir Putin.
For now, such talks are only being held between Washington and Moscow.
The Munich meetings will take place just a few days before Mr Trump convenes the inaugural session of his so-called "Board of Peace" on 19 February in Washington.
Mr Trump initially set up the board to manage post-war Gaza, but it appears now that its purview may extend beyond the Palestinian territory.
Some have criticised it as an apparent rival to the United Nations.