Russian aerial attacks on Ukraine killed two people overnight, Ukrainian officials said, while Russia's defence ministry reported several Ukrainian drones had targeted the capital, Moscow.
The attacks came as Ukrainian President Volodymyr Zelensky prepared to meet US President Donald Trump in New York.
It will be Mr Trump's second time seeing Mr Zelensky since the US leader invited Russian President Vladimir Putin on 15 August to Alaska, a meeting that broke Moscow's isolation in the West but yielded no breakthrough on Ukraine.
Russia has not only kept up its barrage of attacks on Ukraine in the past month but has increasingly raised fears in the West, with drone or air incursions in NATO members Poland, Estonia and Romania.
Mr Zelensky is expected to press Mr Trump to take a harder line and impose long-threatened new sanctions on Russia.
Russia launched three missiles and 115 drones at Ukraine overnight, Kyiv's air force said, the latest in what are daily barrages.
Most drones were intercepted by air defence but officials said one civilian was killed in the southern Zaporizhzhia region and another in the coastal Odesa region.
"Russia continued its terror against the people of Ukraine, targeting the civilian population in multiple regions of the country," Prime Minister Yulia Svyrydenko said on social media.
She renewed calls for Kyiv's allies to send more air defence systems.
"Every delay in strengthening Ukraine's air defence means more lives lost," she said.
Kyiv has stepped up its own wave of retaliatory long-range drone strikes on Russia.
Moscow Mayor Sergei Sobyanin, in posts on the Telegram messaging app, said the drones were destroyed en route to the city over a period of about 12 hours.
Experts were examining debris on the ground, he said.
Flights were delayed and cancelled at Moscow's Sheremetyevo airport, Russia's largest by passenger numbers.
Russian national carrier, Aeroflot, said it planned to fully resume normal operations at the airport by the end of the day.
Russia's Defence Ministry said on Telegram that its anti-aircraft units had destroyed 81 Ukrainian drones, by midnight local time, and another 69 between midnight and 7am local time (5am Irish time).
Mikhail Razvozhayev, the governor of the port of Sevastopol in Crimea, home of Russia's Black Sea fleet, said anti-aircraft units had destroyed at least six drones near the port.
Falling debris had triggered a fire on open ground, but this was extinguished.
The governor of Tula region in central Russia, Dmitry Milyayev, said three drones were downed with no damage or casualties.
Vyacheslav Gladkov, the governor of Belgorod region, which borders Ukraine, said that parents should keep their children at home, and that two shopping centres in the region were being temporarily closed.
Railway attacks
Russia has unleashed a massive wave of attacks on Ukraine's railways since the summer, using new tactics to hit key nodes with long-range drones, the CEO of the state railway company has said.
"Their first aim is to sow panic among passengers, their second aim is to hit the overall economy," Oleksandr Pertsovskyi said in an interview held in a rail carriage at Kyiv's central station.
There did not appear to be a particular focus on targeting military cargo.
"These are all, in essence, strikes on civilian infrastructure," he said.
He added that the network is holding up for now.
Ukrzaliznytsia, the vast state-owned railway company, employs 170,000 people and has been the target of Russian attacks since the start of Russia's invasion three-and-a-half years ago, but attacks have intensified, causing regular delays.
Since the start of the war in February 2022, the railway network has been a lifeline for people moving around Ukraine and out of the country, as all civilian flights have been grounded.
World leaders, from French President Emmanuel Macron to Indian Prime Minister Narendra Modi and former US President Joe Biden, have arrived in wartime Ukraine by train.
The rail company's popular sleeper carriages are seen as a reliable way to travel overnight and arrive early in the morning in cities many hundreds of miles away, until the latest Russian onslaught began to delay passengers by several hours.
The railway is also crucial for transporting military equipment and commercial cargo, although volumes of the latter have dropped significantly in wartime, denting the company's finances.
Mr Pertsovskyi said the attacks on railways, which have hit dozens of substations, were linked to the dramatic increase in long-range drones that Russia's military-industrial complex is producing.
"Previously, they simply did not have sufficient resources for a single combat drone, such as a Shahed, to hunt down a locomotive. Now they can afford to use Shaheds to hit individual locomotives rather than strategic targets," he said.
For now, the railway is recovering from each blow, he added.
The immediate disruption to trains after an attack usually lasts six to 12 hours and electric locomotives are switched out for diesel while power is restored.
Mr Pertsovskyi said disruption had been minimised and the transit of military cargoes had not been impacted.
"It's a marathon ... They strike us, we recover. "They strike us, we recover," he said.
Since the middle of summer, Russia has attacked railway electricity substations and other infrastructure nodes with an average of six to seven long-range Shahed kamikaze drones most nights, according to Mr Pertsovskyi.
"They are acting systematically, knocking out one substation after another or key rail hubs in order to stop passenger trains and sow panic and distrust among the people."
Five or six key rail hubs have been bombarded since the summer, he said.
Reuters could not independently verify the reports.
Russia denies targeting Ukrainian civilians.
The World Bank estimates that roughly 30% of Ukraine's railway is in a "damage-repair" cycle.
Some bridges had been hit many times over by Russian forces throughout the war and repaired each time, but Mr Pertsovskyi declined to specify which ones, citing security reasons.
The company would keep up the pace of repairs, he said.
"If we slow down a little and let the enemy strike and destroy, then they will be even more drawn to the smell of blood," he said.
Mr Trump took office earlier this year vowing that he could end within one day the Ukraine war, which has claimed tens of thousands of lives, and boasted of his personal chemistry with Putin.
Mr Trump acknowledged last week that Mr Putin had "really let me down".
Secretary of State Marco Rubio, last week previewing the talks with Mr Zelensky, said that Mr Trump was not ready to pressure Mr Putin, saying that without him, "there's no one left in the world that could possibly mediate" on Ukraine.
Mr Zelensky will again need to tread carefully with Mr Trump, who - along with Vice President JD Vance - berated the wartime leader in an explosive 28 February meeting at the White House, calling him ungrateful for billions of dollars in US military assistance.
