Renewed fighting in Gaza Stretched into a second day after talks to extend a week-old truce with Hamas collapsed and mediators said Israeli bombardments were complicating attempts to again pause hostilities.
Eastern areas of Khan Younis in southern Gaza came under intense bombardment as the truce deadline lapsed shortly after dawn yesterday, with columns of smoke rising into the sky, journalists in the city said.
Residents took to the road with belongings heaped up in carts, searching for shelter further west.
Israel said its ground, air and naval forces struck more than 200 "terror targets'' in Gaza. The health officials in the coastal strip said Israeli strikes had killed 184 people, wounded at least 589 others and hit more than 20 houses.
The warring sides blamed the other for the collapse of the truce by rejecting terms to extend the daily release of hostages held by militants in exchange for Palestinians held in Israeli jails.
The United Nations said the fighting would worsen an extreme humanitarian emergency. "Hell on Earth has returned to Gaza," said Jens Laerke, spokesperson for the U.N. humanitarian office in Geneva.
"Today, in a matter of hours, scores were reportedly killed and injured. Families were told to evacuate, again. Hopes were dashed," said U.N. aid chief Martin Griffiths, adding that children, women and men of Gaza had "nowhere safe to go and very little to survive on."

A pause that started on 24 November had been extended twice and Israel had said it could continue as long as Hamas released 10 hostages each day. However, after seven days during which women, children and foreign hostages were freed, mediators failed to find a formula to release more, including Israeli soldiers and civilian men.
Israel accuses Hamas of refusing to release all the women it held. A Palestinian official said the breakdown occurred over female Israeli soldiers.
Israel has sworn to annihilate Hamas after a rampage on 7 October in which it says the militant group killed 1,200 people and took 240 hostage.
Israeli assaults have laid waste much of Gaza, which Hamas has ruled since 2007. Palestinian health authorities deemed reliable by the United Nations say more than 15,000Gazans have been killed and thousands are missing.
Qatar says negotiations continuing
Qatar, which has played a central role as mediator, said negotiations were still going on with Israelis and Palestinians to restore the truce, but Israel's renewed bombardment of Gaza had complicated matters.
An Israeli official in Washington said it was a "very high priority" to get as many hostages released as possible.
"And for that, under agreed terms, Israel is willing to give additional pauses," the official said, while adding: "We can negotiate while we still fight."
In the north of Gaza, previously the main war zone, huge plumes of smoke rose above the ruins, seen from across the fence in Israel. Gunfire and explosions rang out above the sound of barking dogs.
Residents and officials from Hamas said its fighters armed with rocket-propelled grenades battled Israeli troops and tanks in Gaza City's Sheikh Radwan neighbourhood in the north.
Sirens blared across southern Israel as militants fired rockets from the coastal enclave into towns. Hamas said it had targeted Tel Aviv, but there were no reports of casualties or damage there.
There were casualties reported in southern Lebanon, another flashpoint of conflict for Israel. A Lebanese official said Israeli shelling killed three people. The Iran-backed Lebanese group, Hezbollah, a Hamas ally, said it had carried out several attacks on Israeli military positions at the border in support of Palestinians.
US and Hamas trade accusations
The United States blamed Hamas for the renewed fighting, saying it had failed to produce a new list of hostages to release.
US Defence Secretary Lloyd Austin said the United States government was working diplomatically to restore the truce.
"We're going to continue to work with Israel and Egypt and Qatar on efforts to re-implement the pause," he told a news conference in California, while blaming Hamas for failing to meet conditions on hostages and for an attack in Jerusalem.
Democratic US Senator Mark Warner, who chairs the Senate Intelligence Committee, said the United States government should be putting pressure on Israel.
"We should be pushing Israel to realise this is not only a military conflict, but it is a conflict for hearts and minds of people in the world and people in United States."
Hamas accused Washington of giving a green light for an Israeli "war of genocide and ethnic cleansing."
"Today, it brazenly repeats the Zionist lies, which hold Hamas responsible for resuming the war and not extending the humanitarian truce," it said in a statement.
Israel said its ground, air and naval forces struck more than 200 "terror targets" in Gaza.
The Palestinian Red Crescent said Israeli forces had stopped all deliveries of aid into Gaza through the Rafah border crossing with Egypt.

COGAT, the Israeli agency for civilian coordination with the Palestinians, said aid agreed under the truce had been stopped but, at Washington's request, "dozens' ' of other trucks with water, food and medical supplies had reached the enclave.
Gazans said they feared the bombing of southern parts of the territory could herald an expansion of the war into areas Israel had previously described as safe.
Leaflets dropped on eastern areas of Khan Younis ordered residents of four towns to evacuate - not to other areas in Khan Younis as in the past, but further south to Rafah.
"You have been warned," said the leaflets, written in Arabic.
Israel released a link to a map showing Gaza divided into hundreds of districts, which it said would be used in future to communicate which areas were safe.