At least 21 people were killed after a blast tore through a Kabul mosque during evening prayers yesterday, Kabul police said.
A police spokesperson said that another 33 people had been injured.
Witnesses said the powerful explosion was heard in a northern Kabul neighbourhood, shattering windows in nearby buildings.
There was no immediate claim of responsibility for the blast and authorities did not publicly assign blame.
The Taliban say they are restoring security to the war-torn country, which has seen an overall drop in violence since the group took over last year.
However, several large attacks, some claimed by the so-called Islamic State, have taken place in urban centres in recent months.
Emergency Hospital, a facility run by an Italian NGO that specialises in treating victims of war, said in a statement it had admitted 27 people, including five children, who had been wounded in the blasts.
Two people were pronounced dead on arrival and a third died in the emergency room, Emergency's Afghanistan country director Stefano Sozza said.
So far this month, the hospital had treated 80 patients from six different mass casualty events, which includes major incidents such as blasts and mass shootings.
"The country is suffering the consequences of a very long conflict that has undermined its future," Mr Sozza said.
