Israeli police clashed with Palestinians for a second night in annexed east Jerusalem, amid mounting tensions over a ban on gatherings and anger fuelled by videos posted of attacks.
The fresh violence came after clashes overnight on Thursday, in which the Palestinian Red Crescent reported at least 105 wounded, of whom around 20 were transferred to hospital, while the Israeli police said 20 officers had been injured.
It had flared outside one of the entrances to the walled Old City, after police had barred access to some areas where Palestinians usually gather in large numbers during the Muslim fasting month of Ramadan.
Tensions were fuelled by the arrival of far-right Jews at the end of a march during which they harassed Palestinians and chanted "death to Arabs".
After calm during daylight hours yesterday, scuffles broke out again as thousands of Muslim worshippers left Al-Aqsa Mosque compound after evening prayers, when they found themselves confronted by dozens of armed police, including officers on horseback.
Clashes broke out between worshippers and police, with water bottles hurled at officers who fired stun grenades to disperse the crowd.
The United States, Israel's ally which under President Joe Biden has encouraged greater rights for Palestinians, said it was "deeply concerned" by the escalation in violence.
"The rhetoric of extremist protestors chanting hateful and violent slogans must be firmly rejected," State Department spokesman Ned Price wrote on Twitter.
The European Union and United Nations also appealed for restraint.
Hundreds of Palestinians also gathered yesterday at the Qalandiya crossing between Jerusalem and the city of Ramallah in the occupied West Bank, police said.
In Bethlehem, also in the West Bank, Palestinians threw stones and petrol bombs towards the tomb of biblical matriarch Rachel, a shrine venerated by Jews and Muslims, police said.
There have been nightly disturbances in the area since the start of Ramadan on 13 April, with Palestinians angry over police blocking access to the promenade around the walls, a popular gathering place after the end of the daytime Ramadan fast.
Meanwhile, three rockets were fired from Gaza last night towards southern Israel, the army said.
One rocket was intercepted by Israel's Iron Dome air defence system and the two others shot down near the barrier between Gaza and Israel, which is heavily guarded by the Israeli army.
Police said that after night prayers at Al-Aqsa mosque on Thursday "hundreds of rioters began disrupting the order violently, including throwing stones and objects at forces".
Stun grenades were fired and water cannon deployed to disperse the "rioters" and force them towards less central areas of east Jerusalem, they said.
The Palestinian presidency condemned "the growing incitement by extremist far-right Israeli settler groups advocating for the killing of Arabs, which in recent days manifested in a wave of attacks against Palestinian civilians in the Old City".
A statement on the official Palestinian news agency Wafa urged the international community to protect Palestinians from the "settler" attacks, which it alleged were encouraged by the Israeli government.
