The British government has given its full backing to British politicians and others sanctioned by China for speaking out in defence of the Uyghur Muslim minority.
"The MPs and other British citizens sanctioned by China today are performing a vital role shining a light on the gross human rights violations being perpetrated against Uyghur Muslims," Prime Minister Boris Johnson tweeted.
"Freedom to speak out in opposition to abuse is fundamental and I stand firmly with them."
China announced sanctions against nine UK individuals and four entities, saying they had "maliciously spread lies and disinformation" over Beijing's treatment of Uyghurs.
Foreign Secretary Dominic Raab called on Beijing to give the United Nations access to the region of Xinjiang if it wants to "credibly rebut claims of human rights abuses".
"We condemn China's attempt to silence those highlighting human rights abuses, at home and abroad, including UK MPs and peers," he said in a tweet.
"While the UK joins the international community to sanction human rights abuses, Chinese govt sanctions its critics."
Justice minister Robert Buckland said "we strongly deprecate" Beijing's announcement, which also targeted a British law firm that has taken up Uyghur rights causes.
Those sanctioned include Iain Duncan Smith, former leader of Britain's ruling Conservative party, along with four groups that have been vocal in driving rights in Xinjiang and Hong Kong higher up Westminster's agenda.
Duncan Smith said it was "our duty to call out the Chinese government's human rights abuses in Hong Kong and their genocide of the Uyghur people".
"Those of us who live free lives under the rule of law must speak for those who have no voice. If that brings the anger of China down upon me then I shall wear that as a badge of honour."
The MPs and other British citizens sanctioned by China today are performing a vital role shining a light on the gross human rights violations being perpetrated against Uyghur Muslims.
— Boris Johnson (@BorisJohnson) March 26, 2021
Freedom to speak out in opposition to abuse is fundamental and I stand firmly with them.
China's Ministry of Foreign Affairs said in a statement: "The United Kingdom (UK) imposed unilateral sanctions on relevant Chinese individuals and entity, citing the so-called human rights issues in Xinjiang.
"This move, based on nothing but lies and disinformation, flagrantly breaches international law and basic norms governing international relations, grossly interferes in China's internal affairs, and severely undermines China-UK relations."
It added that the sanctioned parties would be barred from China - including Hong Kong and Macau.
Their property in the country would be frozen and Chinese citizens and institutions would be banned from dealings with them.
It also warned Britain "not to go further down the wrong path".
The EU, UK, Canada and US sanctioned several members of Xinjiang's political and economic hierarchy this week in a coordinated action over allegations of widespread abuse in the northwestern region.
At least one million Uyghurs and people from other mostly Muslim groups have been held in camps there, according to rights groups, who accuse authorities of forcibly sterilising women and imposing forced labour.
Conservative MPs Nusrat Ghani, Tim Loughton, Tom Tugendhat and Neil O'Brien, and peers Helena Kennedy and David Alton, were also on the list announced by China on Friday.
In a joint statement, Mr Tugendhat and Mr O'Brien called the sanctions "profoundly sinister" for targeting elected lawmakers.
"As British legislators this will not actually affect us hugely, but the point of Beijing's actions is to make others feel threatened, and to have a chilling effect on business people in particular," they said.
Mr Tugendhat further told the BBC that the move was "a direct assault on British democracy and an attempt to silence the people that the British people have chosen to speak for them.
"If that isn't an assault on British sovereignty, I don't know what is."
Ms Ghani told BBC radio that she "won't be intimidated".
"This is a wake-up call for all democratic countries and lawmakers that we will not be able to conduct our day-to-day business without China sanctioning us for just attempting to expose what's happening in Xinjiang and the abuse against the Uyghurs.
"This has now made me even more determined to speak out about the Uyghurs."
China has also launched a PR war on Western brands that have been critical of rights abuses in Xinjiang, with celebrities severing ties with Nike.
Chinese TV stars Wang Yibo and Tan Songyun said they would end all promotional partnerships with Nike, after a year-old company statement was regurgitated online noting it was "very concerned" by the allegations of forced labour.
Earlier this month, EU member states agreed to impose sanctions on four Chinese officials and one state-owned entity over Beijing's crackdown on the Uighur minority.