Thirteen new cardinals have been created by Pope Francis in a ceremony that took place at the Vatican on the eve of the first Sunday of Advent.
Eleven of the cardinals-elect were present for the consistory.
Travel restrictions meant that Cornelius Sim of Brunei and Jose Fuerte Advincula of the Philippines were unable to attend.
They joined the celebration remotely from their dioceses through a digital platform.
Pope Francis urged the new cardinals not to stray away from "journeying on God's road".
The diverse group - whose members hail from Italy, Malta, the Philippines, Chile, Brunei, Mexico and the United States - reflect not only the changing face of the church of 1.3 billion faithful, but also the Jesuit pope's belief in priests focused on the world's poor.
The 72-year-old Archbishop of Washington, Wilton Gregory, told AFP yesterday that he was a "symbolic individual" for being made the first African-American cardinal.
Since Francis' election in 2013, the Argentine pope - the first from the Americas - has created 95 new cardinals in ceremonies known as consistories.
Those named by Pope Francis now make up the majority of those cardinals under the age of 80 who will elect his successor.
That increases the chances that the pope's efforts to make the Roman Catholic Church more inclusive, transparent, and more focused on defending the most vulnerable members of society, may continue after his death.
During the ceremony, Pope Francis warned the new cardinals not to be seduced by their new "eminence" and stray from being "close to the people".
"The scarlet of a cardinal's robes, which is the colour of blood, can, for a worldly spirit, become the colour of a secular 'eminence'," he said. "When you feel that, you will be off the road."
Only about 40 current cardinals, all in masks, were in attendance, sitting spaced apart before a limited audience of guests.
Due to the coronavirus, the tradition of exchanging "a kiss of peace" with the pope and all the other cardinals was suspended.
Nine cardinals in the latest group are under the age of 80 and thus eligible to join a conclave to elect the next pope upon the death or resignation of Francis.
Pope Francis' choices reflect not only a desire to promote non-Europeans within the church, but the pontiff's personal fight against social inequality and poverty.
The Philippines' Cardinal Advincula said he believed the pope chose him to acknowledge Catholics living in far-flung areas from Rome.
"I always thought that the Church has to be closer to the people, especially those that are in the peripheries," Cardinal Advincula told Vatican News last month after being named.
Pope Francis also named the archbishop of Washington DC, Wilton Gregory, the first African-American to become cardinal.
The group of cardinals also includes Mexico's Bishop Emeritus Felipe Arizmendi Esquivel, who has worked among the indigenous population of the poor region of Chiapas, and Archbishop Antoine Kambanda of Rwanda, who lost most of his family in the 1994 genocide.
Francis also named the Archbishop of Santiago, Celestino Aos Braco, in a nod to the challenges ahead in restoring confidence in the Church in Chile in the aftermath of a widespread sex abuse scandal and coverup.
The group of six new Italian cardinals includes Augusto Paolo Lojudice, the current archbishop of Siena, known for his defence of Roma people, and the Franciscan priest Mauro Gambetti, guardian of the Holy Convent of Assisi, the city of Saint Francis.
Tomorrow, Pope Francis will celebrate a traditional mass with exclusively the new cardinals participating.