At least seven people have died when a medical plane crashed in Philadelphia, including six Mexicans aboard the plane and one person who was on the ground, Mexico's president and Philadelphia's mayor have said.
The city's Mayor Cherelle Parker told a press conference that the person who died on the ground had been in a car at the site of the crash.
"Thus far, our count is that there are 19 injured victims," Ms Parker said.
Separately, Mexican President Claudia Sheinbaum said in a post on X that she had asked consular officials to support the families of the six Mexican citizens who were on the plane and died when it crashed.
Jet Rescue Air Ambulance, based in Mexico and licensed to operate in the US, said its aircraft crashed with four crew members, one pediatric medical patient and the patient's mother on board.
The child was a girl on her way home with a final destination of Tijuana, Shai Gold, who works on corporate strategy with Jet Rescue Air Ambulance, told CNN.
Her mother was also aboard, he said.
"We are terribly shocked by this tragic turn of events," Mr Gold said.
"This was a very seasoned crew. We are a leading air ambulance company, we fly 600 to 700 times a year."
He said the company had invested heavily in maintaining its aircraft to the highest international standards and that the plane that crashed had been in excellent flying condition.
"We really don't know what happened," Mr Gold said.
Pennsylvania Governor Josh Shapiro told a press conference at the crash scene that "we know there will be loss in this region".
"We want to offer our thoughts and our serious prayers for those that are grieving at this moment," Mr Shapiro said.
President Donald Trump wrote on social media that it was "so sad to see the plane go down in Philadelphia, Pennsylvania. More innocent souls lost. Our people are totally engaged. First Responders are already being given credit for doing a great job."
The crash follows this week's collision of an American Airlines jet and a US Army Black Hawk helicopter over Washington DC, which killed 67 in the deadliest airplane crash in the US since 2009.
The Federal Aviation Administration said six people were on the Learjet 55 that crashed around 6.30pm local time (11.30pm Irish time).
Local media reported it was near the Roosevelt Mall in northeast Philadelphia and that there were multiple injuries on the ground.
Video aired on local TV stations showed the plane in a sharp dive before hitting the ground and exploding.
Officials said it was not clear what led to the crash.
The weather was cold and rainy and with low visibility when the plane went down.
The air ambulance had left Northeast Philadelphia Airport and was headed to Springfield-Branson National Airport in Missouri, about 1,800km to the southwest, the FAA said in a statement.
A large fire and several fire trucks were visible at the crash scene in images broadcast by the Philadelphia CBS affiliate.
About two hours after the crash the fires were mostly out, according to TV images.
