Theranos founder Elizabeth Holmes has been convicted of defrauding investors in her blood-testing start-up, in a high-profile case seen as an indictment of Silicon Valley culture.

Jurors found Holmes guilty of four counts of tricking investors into pouring money into what she claimed was a revolutionary testing system, after a complex and lengthy trial. They acquitted her of a number of the charges she had faced, and did not reach a verdict on others.

The 37-year-old now faces the possibility of years behind bars, in a case that put on trial the line between start-up hustle and criminal dishonesty.

Holmes had vowed to revolutionise diagnostics with self-service machines that could run an array of tests on just drops of blood, a vision that drew high-profile backers and made her a billionaire by the age of 30.

She was hailed as the next tech visionary on magazine covers and collected mountains of investors' cash, but it all collapsed after Wall Street Journal reporting revealed the machines did not work as promised.

Prosecutors spent 11 weeks presenting over two dozen witnesses, as they painstakingly laid out their argument that Holmes knew her technology did not work as promised and took steps to mislead investors and patients.

She personally put the logos of pharma giants Pfizer and Schering-Plough onto Theranos reports hailing the company's blood-testing technology, which were then shared with investors.

That was done without the firms' permissions, and was a key piece of the prosecution's argument that she deliberately tried to inflate Theranos's credibility in order to win backers.

Elizabeth Holmes: The rise and fall of a Silicon Valley star

Though big-name Theranos investors like Rupert Murdoch and Henry Kissinger were on the witness list, the most prominent backer to take the stand was ex-Pentagon chief Jim Mattis.

The defence called only one significant witness, Holmes herself, as it argued the fallen entrepreneur had genuinely believed in Theranos's vision, invested herself heavily in its success but had simply failed.

Holmes also sought to shift some of the blame to Ramesh "Sunny" Balwani, her boyfriend and whom she had brought in to help run her company.

She fought back tears as she told jurors that Mr Balwani denigrated her and forced himself on her sexually when angry - accusations that he has forcefully denied.

He is due to stand trial separately for his role in the company's operations and has pleaded not guilty.

Beyond the reams of company documents, highly detailed technical questions and Holmes's at-times emotional testimony, there loomed the question of Silicon Valley's very nature.

One of the start-up world's most repeated cliches is "fake it till you make it", where ambitious entrepreneurs with an idea that almost works convince people to invest massive sums of money in the hope that one day it will.

It is exceedingly rare for entrepreneurs of failed Silicon Valley companies - of which there are many - to face fraud prosecution over unrealised promises and unreturned investments.

Some tech world figures, like former Reddit chief Ellen Pao, said sexism may have been a factor in the prosecution, but others argued Holmes had gone too far in trying to prop up her steadily dissolving vision.

After the 2015 Wall Street Journal reporting that questioned whether Theranos's machines worked as promised - and ultimately brought down the company - Holmes went on the offensive in the media.

"First they think you're crazy, then they fight you, then all of the sudden you change the world," she said in a television interview.