The contest at the Oscars in the Best Animated Short Film category could come straight from the pages of a Hollywood script.
The students versus the studios: A graduation project pitched against films from Disney and 20th Century Fox.
Head Over Heels truly is a short taking on giants.
Written and directed by New York-based Timothy Reckart, and produced by Irishwoman Fodhla Cronin O'Reilly, both aged 26, it was made while they were studying at the UK's National Film and Television School.
The pair enlisted a large crew of students to bring Reckart's Rembrandt-inspired vision to life.
Using stop-motion animation, the film captures the emotional distance between a long-married husband and wife, illustrated by one living on the ceiling and one living on the floor.
Nick Park, who created the famous Wallace and Gromit characters for his graduation film at the NFTS 30 years ago, said, "Head Over Heels is one of those stand-out little gems that doesn't come around that often. It's a cleverly conceived but simple idea - a clear and inventively told story - very poignant and full of heart."
Having bagged the Annie Award for Best Student Animated Film, plus a host of international festival awards, the film also won a Motion Picture Sound Editor's Golden Reel Award earlier this week.
It has received rave reviews in the world's film press, as well as the public's vote with over 300,000 hits on YouTube and a strong Facebook following.
Cronin O’Reilly, from the village of Cromane, near Killorglin, Co Kerry, describes the past few weeks as "a whirlwind" and says she's "delighted and overwhelmed " just to be in contention for an Oscar.
But Hollywood loves a good fairytale.
We'll find out tomorrow if this one has an extraordinary ending.