Pharmaceutical company Pfizer is planning to cut around 100 jobs at its plant in Ringaskiddy, Co Cork.
The company said it made the difficult decision due to an anticipated reduction in volume requirements and changes to the small molecule operations at the site.
"Pfizer continuously evaluates its manufacturing network to ensure capacity is effectively utilised based on patient needs, projected product demand, and long-term business objectives," the company said in a statement.
The proposed reductions will impact staff at the Ringaskiddy site during the last quarter of 2026.
"Reducing jobs is always the very last resort and we have been doing all we can to minimise the impact on our people," the company said.
"We are actively engaging with colleagues and their representatives, and all job-related decisions will be made with transparency, respect, and in compliance with all applicable laws."
Pfizer said its sites in Ireland have played a key role in its global network, with over $10 billion invested since operations began in 1969.
"We remain committed to Ireland with approximately 4,500 colleagues in four locations across the country," the company said.