The Dáil has voted to opt into the EU Asylum and Migration Pact by a margin of 79 votes to 72.
The pact was debated in the house both this week and last.
The Government had argued that Ireland must look across the European Union for solutions to rising levels of migration rather than isolate itself.
In March, Minister for Justice Helen McEntee announced that Ireland would opt into the pact, which will introduce legally-binding processing times for International Protection applications.
It will also require a substantial increase in the number of staff processing applications, the building of new accommodation centres, enhanced border security and an increase in the collection of fingerprints.
However the pact has provoked controversy, with critics claiming that it is heavy-handed.
Sinn Féin has said Ireland must opt out of the majority of its provisions, otherwise the hands of future Irish governments will be tied.
Ms McEntee welcomed the Dáil vote.
"This is the best way forward for Ireland and Europe to deal with migration issues together, with faster processing of applications, stronger border security, and faster returns."
Ms McEntee said the pact "will take time to implement but in Ireland we're not waiting and have already introduced improvements to our system."
"We must protect those who need it, where they are fleeing war or persecution, but also be able to easily return people with no entitlement to be here," she added.
