One to watch: Can Alliance take a seat at the expense of the SDLP?
Profile: Despite being a predominately nationalist constituency, almost all the political drama in South Down has centred on the single unionist seat.
The DUP held it through Jim Wells, well-known for his ultra conservative views on social issues such as same-sex marriage and abortion.
He was de-selected by the party in January.
His friend and former party leader Edwin Poots, conscious of a tight battle in his own Lagan Valley constituency, sought the nomination.
But he was passed over in favour of accountant Diane Forsythe, who had previously fought the British General Election for the DUP.
She quit the party over the ousting of former leader Arlene Foster for Mr Poots, but rejoined when Jeffrey Donaldson replaced Edwin Poots just weeks later.
There will be interest in whether all the internal wrangling has any impact on the DUP vote share.
The Alliance Party has been building in this constituency and for a time in 2017 challenged for the final seat which was ultimately taken by the SDLP.
It will be hoping to improve again and is targeting a seat.
The SDLP will miss the presence of a popular former MLA who did not seek re-election.
It's running its other incumbent and a former MLA in the hope of retaining its two seats, but its second seat could be in jeopardy from an Alliance surge.
Sinn Féin is running an incumbent MLA and a new candidate, having deselected its other sitting MLA in favour of a local councillor.
2017 Assembly Election: Sinn Féin 2; SDLP 2: DUP 1
First preference vote share:
Seats Available: 5
Number of candidates: 12
Patrick Brown, Alliance Party
Patrick Clarke, Independent
Sinéad Ennis, Sinn Féin
Diane Forsythe, DUP
Noeleen Lynch, Green Party (NI)
Jill Macauley, UUP
Cathy Mason, Sinn Féin
Paul McCrory, People Before Profit Alliance
Rosemary McGlone, Aontú
Colin McGrath, SDLP
Harold McKee, TUV
Karen McKevitt, SDLP