Government funded research centre AMBER is to provide an extra 350 new research positions over the next six years.
The centre, which has its headquarters at Trinity College Dublin, already employs more than 1,100 people.
The expansion is being delivered with €40 million in funding from 2019 until 2025 through Science Foundation Ireland's (SFI) Research Centres Programme, and €77m in other funding.
Minister of State for Training, Skills, Innovation, Research and Development, John Halligan said: "I congratulate AMBER on all of its success as it move to the next phase.
"SFI Research Centres such as AMBER provide the basis for Ireland to move towards becoming an innovation leader, by providing new thinking and new solutions.
"We have many opportunities, including those I set out in the recently published National Space Strategy for Enterprise, it is important that we invest in excellent research to allow us to take full competitive advantage and deliver this potential."
It is planned that between 2019 and 2025, AMBER will bring together research clusters to address current gaps in knowledge and drive advances in materials science and engineering.
AMBER will also develop research into new sustainable products and technologies for society and solutions for industry.
Its work is aimed at creating new materials and technologies that minimise environmental impact and build a sustainable future.