The Health Service Executive has ordered a formal investigation into the death of a 16-year-old girl at University Hospital Limerick last year.
Aoife Johnston, from Shannon in Co Clare, died from meningitis in the hospital last December.
The HSE said that CEO Bernard Gloster has considered a report, which the agency received this month, into the death.
"The report is significant in its findings about the care of Aoife and the operation of the hospital," the HSE said in a statement.
"Having considered all of the matters, the CEO is satisfied that questions of accountability need to be addressed," the statement added.
"I have appointed the former Chief Justice Mr Justice Frank Clarke (retired) to conduct a formal investigation into all of these matters, to make findings and to report to me," Mr Gloster said.
The investigation is to be "timely but thorough", he added, and its outcome "will inform any further decisions to be made".
Ms Johnston's family said that it is "satisfied" that a more thorough inquiry into the death will be carried out.
A statement, issued by Senior Counsel Damien Tansey on their behalf, said: "We got the report following the review carried out this year, belatedly, and close to the anniversary of her death, tomorrow, December 19th.
"The family welcomed, albeit belatedly, the publication and delivery of the report prepared by the review committee following their investigation.
"Clearly, a lot of questions remain unanswered in the report and the family are very satisfied that a more indepth and forensic investigation will now be conducted under the chairmanship of the retired Chief Justice Frank Clarke.
"Clearly, they are also concerned that whatever needs to be done, following the in-depth forensic investigation, will be done and done in a timely manner so that no other family is faced with the nightmare that is ongoing for the surviving parents and children since this tragedy occurred."
Unreserved apology from HSE
Following Aoife Johnston's death on Monday 19 December 2022, the UL Hospitals Group vowed to conduct a "comprehensive investigation".
In a statement, the group said that a Serious Incident Management Team had been established to carry out a full investigation.
Taoiseach Leo Varadkar had responded that an investigation into Ms Johnston's death should be done thoroughly and as quickly as possible.
This evening, Mr Gloster said: "I will not be in a position to provide any further details at this time, but again take the opportunity on behalf of the HSE, at the time of her first anniversary to apologise unreservedly to Aoife's family".
But he acknowledged that "no words of mine can ever take away their loss".
