Over 12.6 million Covid-19 vaccines have been administered here, according to the HSE.
Its annual report for 2022 showed that 8.1 million primary doses have been given and 4.5 million booster doses.
There was a write off of over €94m on expired vaccines covering over 850,000 vaccines.
These vaccines expired for a range of reasons, including reduced demand and in some cases policy decisions not to use vaccines for certain groups.
The HSE said that a substantial volume of vaccines was purchased to ensure the opportunity to be vaccinated could be availed of by everybody.
It also pointed out that the decision to purchase specific Covid-19 vaccines was not within the control of the HSE and was a Government decision aligned to EU requirements.
To date, the uptake of the primary Covid-19 vaccinations among adults is 97%.
Of those in approved groups, 77% have got a first booster, 33% a second booster and 42% a third booster.
The report also showed that one HSE staff member earned €974,000 last year.
It is understood this may relate to a hospital consultant who did significant additional work to cut waiting lists.
Eight staff earned between €500,000 and €980,000 and this included doctors.
Former HSE chief Paul Reid earned almost €400,000.
The HSE said that one of the primary drivers behind high earnings in the service remained the shortage of consultant staff, particularly in certain specialties like radiology, psychiatry and emergency medicine.
It also said there were a range of payments and allowances which have the potential to increase remuneration significantly, as well as funded waiting list initiatives.
It said that in relation to six cases of the highest earners, this relates to extra commitments required to cover essential services and in one case a payment made on retirement.