An inspection of a nursing home in Co Laois at the end of last year found that 28 members of staff had resigned since the previous August.
The 28 members of staff related to 20 full-time positions at Droimnin Nursing Home in Stradbally.
The home can cater for a maximum of 100 residents.
As a result, the nursing home agreed to a temporary hold on all new admissions, until management were reassured that the staffing complement had stabilised.
HIQA said that the centre's management had undergone significant changes over the past nine months and has had two changes to the person in charge.
As a result, the centre has put in place a recruitment plan and extra measures to minimise the impact on resident care needs.
HIQA said that despite these measures, the inspectors found clear evidence that the turnover in staff is impacting negatively on resident care.
The two-day unannounced inspection over 12 and 13 December last, was triggered following receipt of unsolicited information of concern received by HIQA.