The Fianna Fáil leader, Micheál Martin, has accused Fine Gael and Labour of having failed to "rejuvenate" towns and villages in rural areas.
Speaking on the campaign trail in Castlebar, Co Mayo, Mr Martin described the coalition as a "very Dublin-centric Government" particularly in terms of transport and broadband.
He said the "two-tiered nature of the recovery" had not been felt in the west of the country, adding that "the demise of the Irish town had been staring the Government in the face for the last number of years".
Mr Martin also made a direct appeal to "angry voters" whose trust, he said, had been betrayed by government parties, and he urged them to vote for Fianna Fáil next Friday.
He said he was especially appealing to those who had chosen Labour in 2011. He accused the junior coalition partner of having broken all of its promises, saying it had been humiliated by Fine Gael in "budget after budget".
Mr Martin also criticised Fine Gael strategists for attempting to scare the electorate into voting for the coalition parties.
In relation to the poll to be published in tomorrow's Sunday Times, Mr Martin said he preferred to judge public opinion by the reaction he was receiving on the doorsteps.
He said the feedback on the ground had been "consistent" since the start of the campaign, adding that canvassers and candidates were reporting "a good, warm engagement with the people".
