Nikita Hand has said the court "appeal retraumatised" her but that she can "finally move on" now after Conor McGregor lost his appeal.
He had challenged a High Court jury's finding that he raped Nikita Hand on 9 December 2018 at a hotel in Dublin.
Speaking outside court, Ms Hand said: "I want to begin by thanking my legal team, the Rape Crisis Centre, and the three judges who delivered the decision today.
"I'm also deeply grateful for everyone who supported me and those [who] believed in me and stood by my side throughout this case.
"This appeal has retraumatised me over and over again, being forced to relive it, what happened has had a huge impact on me.
"To every survivor out there, I know how hard it is - but please don't be silenced. You deserve to be heard, you also deserve justice.
"Today I can finally move on and try to heal," added Ms Hand.
Dublin Rape Crisis Centre welcomes judgment
The Dublin Rape Crisis Centre welcomed the Court of Appeal's judgment.
The Centre's Chief Executive Rachel Morrogh said they hoped the ruling closed the door on a "protracted, traumatic and challenging road" for Ms Hand that was "marked by attempts to discredit her, obfuscate the truth and derail her determination to seek justice".
Ms Morrogh said they hoped that lessons and reforms would arise from the case, including a more victim-centred justice system and a shift in the public’s attitudes towards victims of sexual violence.
Ms Hand’s encouragement of other survivors and her understanding for their experience had left a lasting and inspiring impression, she said.
Ms Morrogh said that "Nikita Hand spoke truth to power and now the truth is known to all".
She said the centre anticipated an increase in calls to its 24-hour helpline at 1800 77 88 88 and would have a full complement of counsellors available to support anyone who might need it.
