The Department of Health has reported 380 new Covid-19 cases, while the number of patients in intensive care is unchanged at 13.
Amid the disruption caused by the cyber attack on the Health Service Executive's system, the number of cases may change due to future data validation.
Earlier, the Chief Executive of the HSE said that Ireland is in a stronger position as it faces the threat posed by the Delta variant, but uncertainty and concerns remains.
Speaking on RTÉ's Morning Ireland, Paul Reid said that there are less hospitalisations and more of the population vaccinated, with 36 patients in hospitals with Covid-19 today.
He said the Government will have to weigh up the data and also consider that the Delta variant poses "a real and significant threat" while also "trying to protect the gains made" as it decides on further reopening.
Mr Reid said that 84% of cases of the Delta variant are in the under 45s.
"Thankfully we have vaccinated the most vulnerable," he said, adding that another 58,000 people were vaccinated yesterday.
Mr Reid said that uncertainty around the Delta variant remains, but the UK scenario suggests that increased hospitalisations are likely.
He said that every 37,000 doses administered is another 1% of the population vaccinated, so "everyday counts".
This evening, Taoiseach Micheál Martin said he has been informed that 40% of eligible adults will be fully-vaccinated by the end of today.
Have just been told that 40% of eligible adults will be fully-vaccinated by the end of today.
— Micheál Martin (@MichealMartinTD) June 25, 2021
Great news - and a fantastic achievement by all involved in Ireland's #CovidVaccine rollout.
Meanwhile, another nine countries have been added to the Mandatory Hotel Quarantine list.
The nine states are Dominican Republic, Eritrea, Haiti, Indonesia, Kuwait, Kyrgyzstan, Myanmar, Russia and Tunisia.
The Department of Health said: "People arriving into Ireland having been in or transited through these states in the previous 14 days must enter Mandatory Hotel Quarantine.
"The decision to add to the list of designated States was taken following advice received by the Chief Medical Officer.
"Passengers from these States that arrive in Ireland after 04.00am on Tuesday 29 June are required to enter quarantine in a designated hotel."
Earlier, Mr Reid said while good progress has been made in Limerick in tackling larger Covid-19 case numbers, cases there remain at three times the national rate.
He called on all people in the county to continue to work together and listen to the public health advice as "it works''.
The HSE yesterday recommended to the Catholic Church in the midwest to consider delaying Communion and Confirmation ceremonies.
Mr Reid said that the vaccine progamme will continue to work down through the age groups.
He said that the National Immunisation Advisory Committee has been asked to assess if any remaining AstraZeneca vaccines can be used in other age groups of the population once second doses are given to over 60s.
If you're aged 50 or more, and you haven't had a #COVIDVaccine yet, you can get a single-dose Janssen vaccine at a local pharmacy. Talk to your local pharmacist, or check the list of participating pharmacies ➡ https://t.co/2bgTjdPwyf#ForUsAll pic.twitter.com/hd0v3LXXCt
— HSE Ireland (@HSELive) June 25, 2021
In Northern Ireland, an additional 229 confirmed cases of Covid-19 were reported today.
No further deaths were recorded in the past 24 hours.
As of this morning, there were 16 patients with the virus in hospital, none of whom were in intensive care.
